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小梁切除术与房角切开术的比较:降压效果及术后干预/并发症

[Comparison of trabeculectomy and canaloplasty : Pressure reducing effect and postoperative interventions/complications].

作者信息

Taruttis T, Chankiewitz E, Hammer T

机构信息

Universitäts- und Poliklinik für Augenheilkunde, Ernst-Grube-Str. 40, 06120, Halle, Deutschland.

出版信息

Ophthalmologe. 2018 Feb;115(2):137-144. doi: 10.1007/s00347-017-0449-3.

Abstract

BACKGROUND

Trabeculectomy (TET) is still the most commonly performed surgical treatment in dealing with primary open angle glaucoma (POAG) worldwide. Canaloplasty (CP) as a nonpenetrating surgical procedure has recently become a new option to efficiently reduce intraocular pressure (IOP).

OBJECTIVES

This study compared both surgical procedures concerning the efficacy in IOP reduction. Furthermore we compared IOP fluctuation, postoperative medication, visual acuity, astigmatism and postoperative interventions and complications.

MATERIALS AND METHODS

Retrospectively studied were 32 eyes after canaloplasty and 31 eyes after trabeculectomy. IOP, IOP fluctuation range, visual acuity, astigmatism and glaucoma medication were recorded preoperatively and after a follow-up of 6 and 12 months. In addition we compared postoperative complications and interventions of both surgical procedures.

RESULTS

The mean IOP after canaloplasty was significantly reduced from 16.0 ± 3.5 mm Hg to 12.5 ± 3.3 mm Hg. Trabeculectomy also achieved a significant IOP reduction from 15.3 ± 3.5 mm Hg to 11.0 ± 2.6 mm Hg. Comparing the two surgical procedures there was no evidence for a significant difference in IOP reduction. Trabeculectomy was able to reduce the number of postoperative glaucoma medication substances better than canaloplasty. There was no difference in postoperative visual acuity or astigmatism. Concerning postoperative complications and interventions canaloplasty treatment was associated with a less severe spectrum of complications.

CONCLUSION

Both procedures provide a safe and efficient IOP reduction. Trabeculectomy is able to achieve an even better IOP reduction without application of additional postoperative medication. Canaloplasty requires shorter inpatient stay, less frequent postoperative checkups and interventions as well as a less severe spectrum of complications.

摘要

背景

小梁切除术(TET)仍是全球治疗原发性开角型青光眼(POAG)最常用的外科手术。作为一种非穿透性外科手术,房角成形术(CP)最近已成为有效降低眼压(IOP)的新选择。

目的

本研究比较了两种手术在降低眼压方面的疗效。此外,我们还比较了眼压波动、术后用药、视力、散光以及术后干预和并发症情况。

材料与方法

回顾性研究了32例接受房角成形术的患眼和31例接受小梁切除术的患眼。记录术前以及随访6个月和12个月后的眼压、眼压波动范围、视力、散光和青光眼用药情况。此外,我们比较了两种手术的术后并发症和干预情况。

结果

房角成形术后平均眼压从16.0±3.5 mmHg显著降至12.5±3.3 mmHg。小梁切除术也使眼压显著降低,从15.3±3.5 mmHg降至11.0±2.6 mmHg。比较两种手术,没有证据表明在降低眼压方面存在显著差异。小梁切除术在减少术后青光眼用药种类方面比房角成形术更有效。术后视力或散光没有差异。关于术后并发症和干预,房角成形术治疗相关的并发症谱较轻。

结论

两种手术都能安全有效地降低眼压。小梁切除术在不使用额外术后药物的情况下能够更好地降低眼压。房角成形术住院时间较短,术后检查和干预频率较低,并发症谱也较轻。

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