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在引入糖尿病足多学科团队后减少下肢大截肢手术

Reducing major lower extremity amputations after the introduction of a multidisciplinary team for the diabetic foot.

作者信息

Rubio José Antonio, Aragón-Sánchez Javier, Jiménez Sara, Guadalix Gregorio, Albarracín Agustín, Salido Carmen, Sanz-Moreno José, Ruiz-Grande Fernando, Gil-Fournier Nuria, Álvarez Julia

机构信息

1Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain.

出版信息

Int J Low Extrem Wounds. 2014 Mar;13(1):22-6. doi: 10.1177/1534734614521234.

Abstract

We analyzed the incidence of lower extremity amputations (LEAs) in the 3rd Health Care Area of Madrid before and after the March 2008 introduction of a multidisciplinary team for managing diabetic foot disease. We compared the amputation rates in people with and without diabetes during 2 periods: before (2001-2007) and after (2008-2011) the introduction of a Multidisciplinary Diabetic Foot Unit (MDFU). We also analyzed the trend of the amputation rates by joinpoint regression analysis and measured the annual percentage change (APC). During the study period, 514 nontraumatic LEAs were performed, 374 (73%) in people with diabetes and 140 (27%) in people without the disease. The incidence of LEAs showed a significant reduction in major amputations in people with diabetes, from 6.1 per 100 000 per year (95% confidence interval [CI] = 4.9 to 7.2), in the 2001 to 2007 period, to 4.0 per 100 000 per year (95% CI = 2.6 to 5.5) in the 2008 to 2011 period (P = .020). There were no changes in incidence of minor or total amputations in the diabetic population or in amputations in the nondiabetic population during the study period. Joinpoint regression analysis showed a significant reduction in the incidence of major LEAs in diabetic population with an APC of -6.6% (95% CI = -10.2 to -2.8; P = .003), but there were no other significant changes. This study demonstrates that the introduction of a multidisciplinary team, coordinated by an endocrinologist and a podiatrist, for managing diabetic foot disease is associated with a reduction in the incidence of major amputations in patients with diabetes.

摘要

我们分析了2008年3月在马德里第三医疗区引入多学科团队管理糖尿病足病前后下肢截肢(LEA)的发生率。我们比较了两个时期糖尿病患者和非糖尿病患者的截肢率:引入多学科糖尿病足病单元(MDFU)之前(2001 - 2007年)和之后(2008 - 2011年)。我们还通过连接点回归分析分析了截肢率的趋势,并测量了年度百分比变化(APC)。在研究期间,共进行了514例非创伤性LEA,其中糖尿病患者374例(73%),非糖尿病患者140例(27%)。糖尿病患者的大截肢发生率显著降低,从2001年至2007年期间的每年每10万人6.1例(95%置信区间[CI]=4.9至7.2)降至2008年至2011年期间的每年每10万人4.0例(95%CI = 2.6至5.5)(P = 0.020)。在研究期间,糖尿病患者的小截肢或总截肢发生率以及非糖尿病患者的截肢发生率均无变化。连接点回归分析显示,糖尿病患者的大LEA发生率显著降低,APC为 - 6.6%(95%CI = - 10.2至 - 2.8;P = 0.003),但没有其他显著变化。这项研究表明,由内分泌学家和足病医生协调的多学科团队管理糖尿病足病与糖尿病患者大截肢发生率的降低有关。

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