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多学科团队在慢性难愈性创面诊治中的临床应用

[Clinical application of multidisciplinary team in the diagnosis and treatment of chronic refractory wounds].

作者信息

Wang Liwei, Liu Bingchuan, Qu Yinyin, Wu Changyi, Tian Yun

机构信息

Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, China.

Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2025 Feb 18;57(1):185-191. doi: 10.19723/j.issn.1671-167X.2025.01.028.

Abstract

OBJECTIVE

To explore the application effectiveness of multidisciplinary team (MDT) in the diagnosis and treatment of chronic refractory wounds, and to provide new ideas for optimizing the clinical diagnosis and treatment of such diseases.

METHODS

A retrospective analysis was performed on the clinical data of patients with chronic refractory wounds who underwent surgery at Peking University Third Hospital from January 2015 to October 2023, and a total of 456 patients, including 290 males and 166 females, with an average age of (49.4±16.9) years. According to whether preoperative MDT discussion was conducted, the patients were divided into MDT discussion group and non-MDT discussion group. The overall implementation process of MDT included: Starting and recording with the medical office, collecting data and discussing the initial MDT, informing the patient of the treatment plan and strictly implementing it, and the change of the condition needs to be discussed again by MDT. The general clinical data, anesthesia risk grade, complications (hypertension, diabetes, coronary heart disease), and the etiology and location of chronic refractory wounds between the two groups were compared. The main observational measurements and outcome indicators of treatment effectiveness included the number of surgeries required to achieve wound healing after admission, the recurrence rate after wound healing, the incidence of perioperative complications (pulmonary infection, severe cardiovascular event, vein thrombus embo-lism, cerebral stroke and delirium, .), and patient satisfaction score.

RESULTS

There were 189 patients in the MDT discussion group and 267 patients in the non-MDT discussion group. There was no significant statistical difference in the clinical data, such as age, gender, body mass index, American Society of Anesthesiologists, comorbidities, etiology, and location of chronic refractory wounds between the two groups (>0.05). The average number of surgeries required for wound healing in MDT discussion group and non-MDT discussion group was 2.1±1.1 and 2.8±1.6, respectively, with a statistically significant difference ( < 0.001). This difference was also significant in chronic refractory wounds caused by three etiologies: Diabetic ulcer, infection after trauma or surgery, and non-union after radiotherapy ( < 0.05). The recurrence rate of the patients in the non-MDT discussion group after wound healing was 18.0%, slightly higher than that in the MDT discussion group of 14.3% (>0.05). In terms of perioperative complications, the non-MDT discussion group also had a higher incidence (3.7% . 2.6%), but the difference was not statistically significant (>0.05). In terms of patient satisfaction, the MDT discussion group scored significantly higher (96.5 . 91.1, =0.028).

CONCLUSION

The MDT mode can significantly reduce the number of surgeries for patients with chronic refractory wounds, improve the effectiveness of therapy and increase patient satisfaction. It is a recommended model for optimizing the clinical diagnosis and treatment effectiveness of chronic refractory wounds.

摘要

目的

探讨多学科团队(MDT)在慢性难愈性创面诊治中的应用效果,为优化此类疾病的临床诊治提供新思路。

方法

回顾性分析2015年1月至2023年10月在北京大学第三医院接受手术治疗的慢性难愈性创面患者的临床资料,共456例,其中男性290例,女性166例,平均年龄(49.4±16.9)岁。根据术前是否进行MDT讨论,将患者分为MDT讨论组和非MDT讨论组。MDT的总体实施过程包括:由医务处启动并记录,收集资料并进行初次MDT讨论,向患者告知治疗方案并严格执行,病情变化需再次经MDT讨论。比较两组患者的一般临床资料、麻醉风险分级、并发症(高血压、糖尿病、冠心病)以及慢性难愈性创面的病因和部位。治疗效果的主要观察指标和结局指标包括入院后创面愈合所需手术次数、创面愈合后的复发率、围手术期并发症(肺部感染、严重心血管事件、静脉血栓栓塞、脑卒中和谵妄等)发生率以及患者满意度评分。

结果

MDT讨论组189例,非MDT讨论组267例。两组患者的年龄、性别、体重指数、美国麻醉医师协会分级、合并症、病因及慢性难愈性创面部位等临床资料比较,差异均无统计学意义(>0.05)。MDT讨论组和非MDT讨论组创面愈合平均所需手术次数分别为2.1±1.1次和2.8±1.6次,差异有统计学意义(<0.001)。在糖尿病溃疡、创伤或手术后感染、放疗后不愈合这三种病因导致的慢性难愈性创面中,差异也有统计学意义(<0.05)。非MDT讨论组患者创面愈合后的复发率为18.0%,略高于MDT讨论组的14.3%(>0.05)。围手术期并发症方面,非MDT讨论组发生率也较高(3.7%对2.6%),但差异无统计学意义(>0.05)。患者满意度方面,MDT讨论组评分显著更高(96.5对91.1,P =0.028)。

结论

MDT模式可显著减少慢性难愈性创面患者的手术次数,提高治疗效果,增加患者满意度,是优化慢性难愈性创面临床诊治效果的推荐模式。

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