Neary Casey P, Bush William W, Tiches Deena M, Durham Amy C, Gavin Patrick R
Bush Veterinary Neurology Service, Leesburg, VA.
J Am Anim Hosp Assoc. 2014 May-Jun;50(3):198-202. doi: 10.5326/JAAHA-MS-5992. Epub 2014 Mar 21.
A 12 yr old castrated male mixed-breed dog presented with a 2 wk history of progressive tetraparesis. Neurologic deficits included a short-strided choppy gait in the thoracic limbs and a long-strided proprioceptive ataxia in the pelvic limbs. Withdrawal reflexes were decreased bilaterally in the thoracic limbs. Signs were consistent with a myelopathy of the caudal cervical/cranial thoracic spinal cord (i.e., the sixth cervical [C] vertebra to the second thoracic [T] vertebra). A mass associated with the C6-C7 articular facet on the left side was identified on MRI of the cervical spinal cord. The lesion was hyperintense to spinal cord parenchyma on T2-weighted images, hypointense on T1-weighted images, and there was strong homogenous contrast enhancement. Significant spinal cord compression was associated with the lesion. The mass was removed through a C6-C7 dorsal laminectomy and facetectomy. Histopathology of the mass was consistent with a synovial myxoma of the articular facet. A postoperative MRI showed complete surgical resection. Albeit rare, synovial myxomas should be included in the list of differential diagnoses for neoplasms affecting the vertebral columns in dogs.
一只12岁去势的雄性混血犬出现进行性四肢轻瘫2周病史。神经功能缺损包括胸肢短步幅、急促步态以及盆腔肢长步幅本体感觉性共济失调。双侧胸肢的退缩反射减弱。症状与尾段颈椎/胸段脊髓头端(即第六颈椎[C]至第二胸椎[T])的脊髓病相符。在颈椎脊髓的MRI上发现左侧C6-C7关节面有一个肿块。该病变在T2加权图像上相对于脊髓实质呈高信号,在T1加权图像上呈低信号,并且有强烈的均匀对比增强。病变伴有明显的脊髓压迫。通过C6-C7椎板切除术和关节突切除术切除了肿块。肿块的组织病理学与关节面滑膜黏液瘤相符。术后MRI显示手术完全切除。尽管罕见,但滑膜黏液瘤应列入影响犬脊柱肿瘤的鉴别诊断清单中。