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柬埔寨龙血树组织培养产生的黄酮类化合物。

Flavonoids produced by tissue culture of Dracaena cambodiana.

作者信息

Wang Hui, Luo Guanyong, Wang Jiayuan, Shen Haiyan, Luo Ying, Dai Haofu, Mei Wenli

出版信息

Nat Prod Commun. 2014 Jan;9(1):39-40.

Abstract

Dragon's blood is a traditional medicine used in many countries of many cultures because of its various therapeutic uses, and its main bioactive compounds are flavonoids, which mainly exhibit antitumor and antimicrobial activities. In the process of tissue culture of Dracaena cambodiana, one of its resource plants, red secretion was discovered in the culture when 6-benzylaminopurine was added. Analysis of its constituents by HPLC in comparison with dragon's blood and the standards proved that 17 compounds, including 10 flavonoids, are the same as those in dragon's blood. It is promising that flavonoids from dragon's blood could be produced by tissue culture of its resource plants for the development of new drugs.

摘要

血竭是一种传统药物,由于其具有多种治疗用途,在许多文化的众多国家中都有使用,其主要生物活性化合物是黄酮类化合物,主要表现出抗肿瘤和抗菌活性。在其资源植物之一柬埔寨龙血树的组织培养过程中,当添加6-苄基腺嘌呤时,在培养物中发现了红色分泌物。通过高效液相色谱法(HPLC)对其成分与血竭及标准品进行比较分析,证明其中17种化合物,包括10种黄酮类化合物,与血竭中的化合物相同。通过其资源植物的组织培养来生产血竭中的黄酮类化合物以开发新药是很有前景的。

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