培养的基底细胞癌的生长和抗原特性
Growth and antigenic characteristics of basal cell carcinoma in culture.
作者信息
Bradbeer M, Bourne A J, Ayberk H, Tang S K, Marks R
机构信息
Monash University Department of Medicine, Melbourne, Australia.
出版信息
Arch Dermatol Res. 1988;280(4):228-34. doi: 10.1007/BF00513962.
PMID:2466442
Abstract
Basal cell carcinomas (BCCs) were cultured using an explant method and compared with normal cultured skin. Immunohistochemical staining revealed reduced beta 2 microglobulin uptake by BCCs in frozen section, but normal staining of the tumours in culture. In culture, fibronectin was detected on the cell surface of normal keratinocytes but not on BCCs. The above differences may explain some of the behaviour of BCCs in vivo.
摘要
采用外植体培养法培养基底细胞癌（BCC），并与正常培养的皮肤进行比较。免疫组织化学染色显示，在冰冻切片中BCC摄取β2微球蛋白减少，但培养的肿瘤染色正常。在培养过程中，在正常角质形成细胞的细胞表面检测到纤连蛋白，而在BCC上未检测到。上述差异可能解释了BCC在体内的一些行为。
Zotero 插件