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在接受重大癌症手术的患者中,是否有“7 月效应”的证据?

Is there any evidence of a "July effect" in patients undergoing major cancer surgery?

机构信息

The Center for Outcomes Research and Analytics, Vattikuti Urology Institute, Detroit, Mich.

The Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, University of Montreal, Montréal, Que.

出版信息

Can J Surg. 2014 Apr;57(2):82-8. doi: 10.1503/cjs.002713.

Abstract

BACKGROUND

The "July effect" refers to the phenomenon of adverse impacts on patient care arising from the changeover in medical staff that takes place during this month at academic medical centres in North America. There has been some evidence supporting the presence of the July effect, including data from surgical specialties. Uniformity of care, regardless of time of year, is required for patients undergoing major cancer surgery. We therefore sought to perform a population-level assessment for the presence of a July effect in this field.

METHODS

We used the Nationwide Inpatient Sample to abstract data on patients undergoing 1 of 8 major cancer surgeries at academic medical centres between Jan. 1, 1999, and Dec. 30, 2009. The primary outcomes examined were postoperative complications and in-hospital mortality. Univariate analyses and subsequently multivariate analyses, controlling for patient and hospital characteristics, were performed to identify whether the time of surgery was an independent predictor of outcome after major cancer surgery.

RESULTS

On univariate analysis, the overall postoperative complication rate, as well as genitourinary and hematologic complications specifically, was higher in July than the rest of the year. However, on multivariate analysis, only hematologic complications were significantly higher in July, with no difference in overall postoperative complication rate or in-hospital mortality for all 8 surgeries considered separately or together.

CONCLUSION

On the whole, the data confirm an absence of a July effect in patients undergoing major cancer surgery.

摘要

背景

“七月效应”是指在北美的学术医疗中心,由于医疗人员在 7 月更替,对患者护理产生不利影响的现象。有一些证据支持“七月效应”的存在,包括来自外科专业的数据。无论在一年中的哪个时候,接受重大癌症手术的患者都需要统一的护理。因此,我们试图在这一领域进行人群水平的评估,以确定是否存在“七月效应”。

方法

我们使用全国住院患者样本,从 1999 年 1 月 1 日至 2009 年 12 月 30 日期间,在学术医疗中心接受 8 种主要癌症手术之一的患者中提取数据。主要观察结果是术后并发症和住院期间死亡率。进行了单变量分析,随后进行了多变量分析,控制了患者和医院的特征,以确定手术时间是否是主要癌症手术后结局的独立预测因素。

结果

在单变量分析中,7 月的总体术后并发症发生率,特别是泌尿生殖系统和血液学并发症的发生率高于其他月份。然而,在多变量分析中,只有血液学并发症在 7 月显著升高,而所有 8 种手术分别或一起考虑时,总体术后并发症发生率或住院死亡率没有差异。

结论

总的来说,数据证实了在接受重大癌症手术的患者中不存在“七月效应”。

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