Rudd Nancy A, Frommelt Michele A, Tweddell James S, Hehir David A, Mussatto Kathleen A, Frontier Katherine D, Slicker Julie A, Bartz Peter J, Ghanayem Nancy S
Section of Cardiology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wis; Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, Wis.
Section of Cardiology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wis; Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, Wis.
J Thorac Cardiovasc Surg. 2014 Oct;148(4):1540-7. doi: 10.1016/j.jtcvs.2014.02.038. Epub 2014 Feb 14.
Infants who undergo Norwood stage 1 palliation (S1P) continue with high-risk circulation until stage 2 palliation (S2P). Routine care during the interstage period is associated with 10% to 20% mortality. This report illustrates the sustained reduction of interstage mortality over 10 years associated with use of home monitoring.
Daily monitoring of oxygen saturation and weight was done for all patients discharged to home after S1P. Notification of the care team occurred for oxygen saturation<75% or >90%, weight gain<20 g over 3 days, weight loss>30 g, or intake<100 cc/kg/d. Breach of these criteria marked an interstage event. Interstage outcomes are reported. Patient characteristics and perioperative variables were compared between patients with and without interstage events.
Over 10 years, 157 patients were discharged after S1P with home monitoring. Interstage survival was 98%. Breach of home criteria occurred in 59% (93 out of 157), with violation of oxygen saturation<75% the most common event. Patient characteristics, operative data, and early postoperative morbidity did not differ between patients with and without events.
Home monitoring after S1P is associated with excellent interstage survival. Although a breach of monitoring criteria occurred in more than half of patients, our analysis failed to identify independent predictors of interstage events. Analysis of variables predicting mortality could not be assessed due to the low frequency of death in this cohort. Failure to identify specific variables for interstage events suggests that home monitoring, as part of an interstage surveillance program, should be applied to all S1P hospital survivors.
接受诺伍德一期姑息手术(S1P)的婴儿在二期姑息手术(S2P)之前一直处于高风险循环状态。两期手术间期的常规护理死亡率为10%至20%。本报告说明了与家庭监测相关的两期手术间期死亡率在10年期间持续下降。
对所有在S1P后出院回家的患者进行每日血氧饱和度和体重监测。当血氧饱和度<75%或>90%、3天内体重增加<20克、体重减轻>30克或摄入量<100 cc/kg/d时,通知护理团队。违反这些标准即标志着两期手术间期事件。报告两期手术间期结果。比较发生和未发生两期手术间期事件的患者的患者特征和围手术期变量。
在10年期间,157例患者在S1P后出院并接受家庭监测。两期手术间期生存率为98%。59%(157例中的93例)违反了家庭监测标准,其中血氧饱和度<75%是最常见的违规事件。发生和未发生事件的患者之间的患者特征、手术数据和术后早期发病率无差异。
S1P后进行家庭监测与良好的两期手术间期生存率相关。尽管超过一半的患者违反了监测标准,但我们的分析未能确定两期手术间期事件的独立预测因素。由于该队列中的死亡频率较低,无法评估预测死亡率的变量。未能确定两期手术间期事件的特定变量表明,作为两期手术间期监测计划一部分的家庭监测应适用于所有S1P术后存活出院的患者。