Shamim Thorakkal
J Ayub Med Coll Abbottabad. 2012 Jul-Dec;24(3-4):210-1.
Peripheral ossifying fibroma is a benign neoplasm that usuallydevelops from gingiva, presenting as an exophytic smooth surfaced pink or red nodular mass that is sessile or is less frequently seen on a pedicle. From the Indian perspective, it is usually noticed in 5th-6th decades of life with female predilection. Microscopically, the tumour shows stratified squamous epithelium and highly cellular fibrous stroma, sparse endothelial proliferation with fibroblasts and dystrophic calcifications. It has to be differentiated histopathologically from pyogenic granuloma, fibroma, peripheral giant cell granuloma, peripheral odontogenic fibroma and fibrous hyperplasia. A case of peripheral ossifying fibroma of maxillary gingiva in a 55-year-old Indian woman is reported.
外周骨化性纤维瘤是一种良性肿瘤，通常起源于牙龈，表现为外生性、表面光滑的粉红色或红色结节状肿物，可为无蒂型，较少见有蒂型。从印度的情况来看，通常在50至60岁发病，女性更为多见。显微镜下，肿瘤表现为复层鳞状上皮和细胞丰富的纤维性间质，伴有稀疏的内皮细胞增生、成纤维细胞和营养不良性钙化。必须通过组织病理学将其与化脓性肉芽肿、纤维瘤、外周巨细胞肉芽肿、外周牙源性纤维瘤和纤维增生相鉴别。本文报道了一名55岁印度女性上颌牙龈外周骨化性纤维瘤的病例。
