Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology , Koganei, Tokyo 184-8588, Japan.
J Am Chem Soc. 2014 Apr 16;136(15):5555-8. doi: 10.1021/ja500841f. Epub 2014 Apr 4.
The enantioselective synthesis of azahelicenes and S-shaped double azahelicenes has been achieved via the Au-catalyzed sequential intramolecular hydroarylation of alkynes. The use of excess AgOTf toward a Au(I) complex is crucial for this transformation. Interestingly, the circularly polarized luminescence activity of the S-shaped double azahelicenes was significantly higher than that of the azahelicenes.
通过金催化的炔烃顺序分子内氢芳化反应，实现了氮杂薁和 S 型双氮杂薁的对映选择性合成。该转化中使用过量的 AgOTf 对于 Au(I) 配合物至关重要。有趣的是，S 型双氮杂薁的圆偏振发光活性明显高于氮杂薁。
