Cheng Wenjun, Xu Haijun, Xiao Zhihong, Ren Yijun, Zheng Qiong, Kan Wusheng
Pu'ai Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China. E-mail:
Nan Fang Yi Ke Da Xue Xue Bao. 2014 Mar;34(3):438-40.
To study the effect of autologous drained blood reinfusion on hidden blood loss and limb swelling following rivaroxaban anticoagulation for primary total hip arthroplasty.
From May, 2011 to October, 2012, 98 patients undergoing primary unilateral total hip arthroplasty received rivaroxaban therapy for prevention of deep venous thrombosis (DVT). Forty-five of the patients used a drained blood reinfusion device (group A) and 53 patients did not (group B). Hidden blood loss and the maximal changes of postoperative circumferential length of the mid-thigh were measured and compared between the two groups.
The mean total blood loss, the hidden blood loss, and the maximal changes of postoperative thigh circumference were 1591.1∓337.3 ml, 1591.1∓337.3 ml, and 5.1∓2.8 cm in group A, as compared to 1374.5∓317.3 ml, 467∓96.8 ml, 3.9∓1.4 cm in group B, respectively. The two groups showed a significant difference in the maximal changes of postoperative mid-thigh circumference (P<0.01) but not in hidden blood loss (P>0.05).
Reinfusion of autologous drained blood does not affect hidden blood loss but can increase limb swelling following primary total hip arthroplasty with rivaroxaban anticoagulation.
研究自体引流血回输对利伐沙班抗凝治疗初次全髋关节置换术后隐性失血及肢体肿胀的影响。
2011年5月至2012年10月,98例行初次单侧全髋关节置换术的患者接受利伐沙班预防深静脉血栓形成(DVT)治疗。其中45例患者使用引流血回输装置(A组),53例患者未使用(B组)。测量并比较两组患者的隐性失血量及术后大腿中部周径的最大变化值。
A组患者的平均总失血量、隐性失血量及术后大腿周径最大变化值分别为1591.1±337.3 ml、1591.1±337.3 ml、5.1±2.8 cm,B组分别为1374.5±317.3 ml、467±96.8 ml、3.9±1.4 cm。两组术后大腿中部周径最大变化值差异有统计学意义(P<0.01),但隐性失血量差异无统计学意义(P>0.05)。
自体引流血回输不影响初次全髋关节置换术利伐沙班抗凝治疗后的隐性失血,但可增加肢体肿胀。