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经导管主动脉瓣植入术后患者生活质量的短期和中期改善:一项单中心研究。

Short- and intermediate-term improvement of patient quality of life after transcatheter aortic valve implantation: a single-centre study.

作者信息

Kleczyński Paweł, Bagieński Maciej, Sorysz Danuta, Rzeszutko Lukasz, Trębacz Jarosław, Tomala Marek, Sobczyński Robert, Dziewierz Artur, Surdacki Andrzej, Dudek Dariusz

机构信息

Institute of Cardiology, Krakow, Poland.

出版信息

Kardiol Pol. 2014;72(7):612-6. doi: 10.5603/KP.a2014.0065. Epub 2014 Mar 27.

DOI:10.5603/KP.a2014.0065
PMID:24671914
Abstract

BACKGROUND

Transcatheter aortic valve implantation (TAVI) is a treatment option for elderly high-risk patients with symptomatic severe aortic stenosis. Improvement of quality of life (QoL) is a relevant issue in this group of patients.

AIM

To assess changes in QoL after TAVI.

METHODS

Forty patients who underwent TAVI in our institution were included in this QoL study. All subjects were screened for TAVI in a standard fashion, including QoL assessment with the EQoL (EQ-5D-3L). The pre- and postprocedural scores obtained up to a 12-month follow-up were assessed.

RESULTS

Median of logistic EuroScore I was 21.5% (13.5-26.75%), and Society of Thoracic Surgeons score was 5.5% (4.0-10.75%). Comparison of baseline values with follow-up data at one, six and 12 months after TAVI showed significant improvement of QoL (p < 0.001). Visual Analogue Scale score (VAS score) was assessed. There was an incremental increase in VAS score during follow-up (p < 0.001). Median of six-minute walk test distance at baseline was 200 m (IQR 150-300) and 325 m (IQR 250-400) 12 months after TAVI (p < 0.001).

CONCLUSIONS

TAVI provides improved QoL and effectively relieves symptoms.

摘要

背景

经导管主动脉瓣植入术(TAVI)是有症状的重度主动脉瓣狭窄老年高危患者的一种治疗选择。生活质量(QoL)的改善是这类患者的一个相关问题。

目的

评估TAVI术后生活质量的变化。

方法

本生活质量研究纳入了在我们机构接受TAVI的40例患者。所有受试者均以标准方式接受TAVI筛查,包括使用欧洲五维健康量表(EQ-5D-3L)进行生活质量评估。评估了直至12个月随访期获得的术前和术后评分。

结果

欧洲心脏手术风险评估系统(EuroScore)I的中位数为21.5%(13.5 - 26.75%),胸外科医师协会(STS)评分中位数为5.5%(4.0 - 10.75%)。将TAVI术后1个月、6个月和12个月的基线值与随访数据进行比较,结果显示生活质量有显著改善(p < 0.001)。评估了视觉模拟量表(VAS)评分。随访期间VAS评分逐渐升高(p < 0.001)。基线时六分钟步行试验距离的中位数为200 m(四分位间距150 - 300),TAVI术后12个月为325 m(四分位间距250 - 400)(p < 0.001)。

结论

TAVI可改善生活质量并有效缓解症状。

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