Department of Breast Surgery, The Second Affiliated Hospital of Dalian Medical University, Shahekou District, Dalian, Liaoning Province, People's Republic of China.
Onco Targets Ther. 2014 Mar 18;7:435-40. doi: 10.2147/OTT.S57831. eCollection 2014.
Metastasis of breast cancer into the gastrointestinal tract happens rarely. The diagnosis of this kind of disease is difficult because of the nonspecific symptoms and the long interval between primary manifestations and recurrence. Awareness of this condition may lead to an accurate diagnosis and an earlier initiation of systemic treatment, thus avoiding unnecessary surgical intervention. In this paper, we report a rare case of a patient with tubulolobular carcinoma metastases to the colon, presenting with abdominal pain, discomfort, and weight loss. The patient underwent radical mastectomy and received postoperative radiotherapy and chemotherapy. Ten years later, she presented with gastrointestinal tract symptoms. Surgery combined with systemic treatment was chosen for the colon lesion. Immunohistochemical staining suggested a breast origin. The patient was still living 24 months after the diagnosis of the metastasis. This is the fourth case report in our literature review.
乳腺癌转移至胃肠道的情况较为罕见。由于此类疾病的症状无特异性，且首发表现与复发之间的间隔较长，因此诊断较为困难。对这种情况的认识可能会导致准确的诊断，并更早地开始全身性治疗，从而避免不必要的手术干预。本文报道了一例罕见的管状小叶癌转移至结肠的病例，该患者表现为腹痛、不适和体重减轻。患者接受了根治性乳房切除术，并接受了术后放疗和化疗。十年后，她出现了胃肠道症状。选择手术联合全身治疗来处理结肠病变。免疫组化染色提示来源于乳腺。在诊断出转移后，患者仍存活 24 个月。这是我们文献复习中的第四例报告。
