Signorelli Carlo, Pomponi-Formiconi Donatella, Nelli Fabrizio, Pollera Camillo Francesco
Medical Oncology Unit, Department of Oncology-Hematology, Belcolle Hospital, Viterbo, Italy.
Tumori. 2005 Sep-Oct;91(5):424-7. doi: 10.1177/030089160509100509.
Metastatic involvement of the extrahepatic digestive system is rare. We here report the case of a 62-year-old woman who presented with a bowel obstruction related to a metastasis of breast cancer occurring 12 years after a mastectomy for lobular carcinoma. No other distant metastases were detected except for two nodules of 20 and 5 mm on the right chest wall. Biopsy of the larger nodule showed a lobular carcinoma. The patient underwent a right hemicolectomy and then received chemotherapy combined with letrozole, resulting in a partial response. The literature revealed only a few cases of breast cancer metastatic to the colon. Patients with known breast cancer, particularly of the lobular histological type, who present with specific or less specific abdominal symptoms or signs such a microcytic anemia, should be endoscopically explored in order to detect possible metastases of the primary breast tumor.
肝外消化系统的转移累及很少见。我们在此报告一例62岁女性病例，该患者因小叶癌乳房切除术后12年发生的乳腺癌转移而出现肠梗阻。除右胸壁有两个直径分别为20毫米和5毫米的结节外，未检测到其他远处转移。较大结节的活检显示为小叶癌。患者接受了右半结肠切除术，然后接受了来曲唑联合化疗，结果部分缓解。文献仅报道了少数乳腺癌转移至结肠的病例。已知患有乳腺癌，尤其是小叶组织学类型的患者，若出现特定或不太特定的腹部症状或体征，如小细胞贫血，应进行内镜检查，以检测原发性乳腺肿瘤可能的转移情况。
