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比较系统性红斑狼疮、类风湿关节炎患者及健康人群中基于女性的避孕方法。

Comparing female-based contraceptive methods in patients with systemic lupus erythematosus, rheumatoid arthritis and a healthy population.

作者信息

Dalkilic Ediz, Tufan Ayse Nur, Oksuz Mustafa Ferhat, Sahbazlar Mustafa, Coskun Belkis Nihan, Seniz Nihan, Pehlivan Yavuz, Inanc Murat

机构信息

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Uludag University, Istanbul, Turkey.

出版信息

Int J Rheum Dis. 2014 Jul;17(6):653-7. doi: 10.1111/1756-185X.12338. Epub 2014 Mar 27.

Abstract

AIM

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is 10 times more prevalent in women, particularly those of reproductive age. The varying effects of pregnancy on SLE and the differences between available SLE treatments make pregnancy timing and contraceptive methods significant. We aimed to determine the contraceptive methods used by SLE patients in the north-west part of Turkey, and compared them with those used by rheumatoid arthritis (RA) patients and healthy controls.

METHOD

The study was comprised of 113 SLE patients, and 84 RA patients at the Rheumatology Outpatient Clinic of Uludag University Medical Faculty.

RESULTS

Twenty-three (20.3%) out of 113 SLE patients, 18 (21.4%) out of 84 RA patients and 17 (18.6%) out of 92 healthy controls did not use any contraceptive methods. Use of the withdrawal and condom methods was more common among SLE patients, accounting for 61% (withdrawal 32.7%, condom 28.3%). Moreover, 52% of SLE and 50% of RA patients were neither given information about contraceptive methods nor offered a suggested method, compared to 34% in the health control group.

CONCLUSIONS

The prevalence of oral contraceptive use is low in Turkey; notwithstanding the withdrawal and condom methods, which are frequently used despite their high failure risk. Although pregnancy timing is of great importance for SLE patients, necessary information and recommendations concerning contraceptive methods have been ignored and the use of effective methods is not a priority.

摘要

目的

系统性红斑狼疮(SLE)是一种全身性自身免疫性疾病,在女性中更为常见,尤其是育龄女性,其患病率是男性的10倍。妊娠对SLE的影响各异,且现有SLE治疗方法存在差异,这使得妊娠时机和避孕方法至关重要。我们旨在确定土耳其西北部SLE患者使用的避孕方法,并将其与类风湿关节炎(RA)患者和健康对照者使用的方法进行比较。

方法

该研究纳入了乌鲁达大学医学院风湿病门诊的113例SLE患者和84例RA患者。

结果

113例SLE患者中有23例(20.3%)、84例RA患者中有18例(21.4%)以及92例健康对照者中有17例(18.6%)未使用任何避孕方法。SLE患者中使用体外排精和避孕套方法更为常见,占61%(体外排精32.7%,避孕套28.3%)。此外,52%的SLE患者和50%的RA患者既未得到避孕方法的相关信息,也未获得推荐方法,而健康对照组这一比例为34%。

结论

在土耳其,口服避孕药的使用率较低;尽管体外排精和避孕套方法失败风险高,但仍被频繁使用。尽管妊娠时机对SLE患者非常重要,但关于避孕方法的必要信息和建议被忽视,有效方法的使用并非优先事项。

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