SPARI 维拉佐酮的作用机制：5-羟色胺 1A 部分激动剂和再摄取抑制剂。

Mechanism of action of the SPARI vilazodone: serotonin 1A partial agonist and reuptake inhibitor.

出版信息

CNS Spectr. 2014 Apr;19(2):105-9. doi: 10.1017/S1092852914000169.

Abstract

Vilazodone is an antidepressant with a novel mechanism of pharmacologic action: serotonin partial agonist reuptake inhibitor (SPARI).

摘要

维拉佐酮是一种具有新型作用机制的抗抑郁药

血清素部分激动剂再摄取抑制剂（SPARI）。

相似文献

Mechanism of action of the SPARI vilazodone: serotonin 1A partial agonist and reuptake inhibitor.SPARI 维拉佐酮的作用机制：5-羟色胺 1A 部分激动剂和再摄取抑制剂。

CNS Spectr. 2014 Apr;19(2):105-9. doi: 10.1017/S1092852914000169.

Vilazodone: a 5-HT1A receptor agonist/serotonin transporter inhibitor for the treatment of affective disorders.维拉佐酮：一种 5-HT1A 受体激动剂/5-羟色胺转运体抑制剂，用于治疗情感障碍。

CNS Neurosci Ther. 2009 Summer;15(2):107-17. doi: 10.1111/j.1755-5949.2008.00067.x.

Mechanism of action of the bimodal antidepressant vilazodone: evidence for serotonin1A-receptor-mediated auto-augmentation of extracellular serotonin output.双峰抗抑郁药维拉佐酮的作用机制：5-羟色胺1A受体介导的细胞外5-羟色胺输出自身增强的证据。

Psychopharmacology (Berl). 2014 Jun;231(12):2547-58. doi: 10.1007/s00213-013-3428-7. Epub 2014 Jan 14.

Electrophysiological evidence for rapid 5-HT₁A autoreceptor inhibition by vilazodone, a 5-HT₁A receptor partial agonist and 5-HT reuptake inhibitor.电生理学证据表明，维拉佐酮（一种 5-HT₁A 受体部分激动剂和 5-HT 再摄取抑制剂）可快速抑制 5-HT₁A 自身受体。

Eur J Pharmacol. 2013 Aug 15;714(1-3):359-65. doi: 10.1016/j.ejphar.2013.07.014. Epub 2013 Jul 16.

Vilazodone (Viibryd)--a new antidepressant.维拉唑酮（维思通）——一种新型抗抑郁药。

Med Lett Drugs Ther. 2011 Jul 11;53(1368):53-4.

A new antidepressant.

Behav Healthc. 2011 Sep;31(6):39-40.

Drug evaluation: Vilazodone--a combined SSRI and 5-HT1A partial agonist for the treatment of depression.药物评价：维拉唑酮——一种用于治疗抑郁症的5-羟色胺再摄取抑制剂（SSRI）与5-羟色胺1A（5-HT1A）部分激动剂的复方制剂

IDrugs. 2007 Mar;10(3):193-201.

Vilazodone approved for major depression.维拉唑酮获批用于治疗重度抑郁症。

Am J Health Syst Pharm. 2011 Mar 1;68(5):366. doi: 10.2146/news110009.

Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression.维拉唑酮，一种新型的双重作用血清素抗抑郁药，用于治疗重度抑郁症。

Expert Opin Investig Drugs. 2009 Nov;18(11):1753-64. doi: 10.1517/13543780903286396.

The discovery and development of vilazodone for the treatment of depression: a novel antidepressant or simply another SSRI?维拉佐酮治疗抑郁症的发现和研发：新型抗抑郁药还是仅仅是另一种 SSRI？

Expert Opin Drug Discov. 2013 Dec;8(12):1529-39. doi: 10.1517/17460441.2013.855195. Epub 2013 Nov 7.

引用本文的文献

Treating depression in patients with borderline personality disorder: clinical clues on the use of antidepressants.治疗边缘型人格障碍患者的抑郁症：使用抗抑郁药的临床线索

Ann Gen Psychiatry. 2024 May 30;23(1):21. doi: 10.1186/s12991-024-00507-z.

SSRIs in the Treatment of Depression: A Pharmacological CUL-DE-SAC?选择性5-羟色胺再摄取抑制剂治疗抑郁症：一条药理学死胡同？

Curr Top Behav Neurosci. 2024;66:1-19. doi: 10.1007/7854_2023_447.

Treating depression in clinical practice: new insights on the multidisciplinary use of trazodone.临床实践中抑郁症的治疗：曲唑酮多学科应用的新见解

Front Psychiatry. 2023 Aug 15;14:1207621. doi: 10.3389/fpsyt.2023.1207621. eCollection 2023.

Recent Developments in Pharmacotherapy of Depression: Bench to Bedside.抑郁症药物治疗的最新进展：从实验台到病床边

J Pers Med. 2023 Apr 29;13(5):773. doi: 10.3390/jpm13050773.

Vilazodone for Major Depression in Adults: Pharmacological Profile and an Updated Review for Clinical Practice.伏硫西汀用于成人重度抑郁症：药理学概况及临床实践的最新综述

Neuropsychiatr Dis Treat. 2022 Jun 14;18:1175-1193. doi: 10.2147/NDT.S279342. eCollection 2022.

"Novel Psychopharmacology for Depressive Disorders".《抑郁障碍的新型精神药理学》

Adv Exp Med Biol. 2021;1305:449-461. doi: 10.1007/978-981-33-6044-0_22.

Repurposing Known Drugs as Covalent and Non-covalent Inhibitors of the SARS-CoV-2 Papain-Like Protease.将已知药物重新用作新型冠状病毒木瓜样蛋白酶的共价和非共价抑制剂

Front Chem. 2020 Nov 16;8:594009. doi: 10.3389/fchem.2020.594009. eCollection 2020.

Neurochemical and behavioural effects of hypidone hydrochloride (YL-0919): a novel combined selective 5-HT reuptake inhibitor and partial 5-HT agonist.盐酸海吡酮（YL-0919）的神经化学和行为学效应：一种新型的5-羟色胺再摄取抑制剂与5-羟色胺部分激动剂的组合药物。

Br J Pharmacol. 2017 May;174(9):769-780. doi: 10.1111/bph.13675. Epub 2017 Mar 21.

Vilazodone for the Treatment of Depression: An Update.伏硫西汀治疗抑郁症：最新进展

Chonnam Med J. 2016 May;52(2):91-100. doi: 10.4068/cmj.2016.52.2.91. Epub 2016 May 20.

Vilazodone for the treatment of major depressive disorder: an evidence-based review of its place in therapy.伏硫西汀治疗重度抑郁症：对其在治疗中地位的循证综述

Core Evid. 2015 Apr 20;10:49-62. doi: 10.2147/CE.S54075. eCollection 2015.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

SPARI 维拉佐酮的作用机制：5-羟色胺 1A 部分激动剂和再摄取抑制剂。

Mechanism of action of the SPARI vilazodone: serotonin 1A partial agonist and reuptake inhibitor.

出版信息

维拉佐酮是一种具有新型作用机制的抗抑郁药

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献