Grissom William A, Cao Zhipeng, Does Mark D
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, USA; Vanderbilt University Institute of Imaging Science, Nashville, TN, USA.
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Vanderbilt University Institute of Imaging Science, Nashville, TN, USA.
J Magn Reson. 2014 May;242:189-96. doi: 10.1016/j.jmr.2014.02.012. Epub 2014 Mar 6.
A new mathematical treatment and algorithm for the design of |B1(+)|-selective RF excitation pulses is presented and validated. The algorithm is based on a rotated Shinnar-Le Roux pulse design algorithm, wherein the pulse's frequency modulation waveform is directly designed by the algorithm, and its amplitude and sign modulation waveform takes the place of the gradient field. A new pulse configuration is described that enables excitation of large tip-angle slice-selective profiles. Experiments were performed to validate the pulses, and simulations were performed to characterize the pulses' sensitivity to off-resonance, and to compare them to adiabatic (BIR-4) pulses.
提出并验证了一种用于|B1(+)|选择性射频激励脉冲设计的新数学处理方法和算法。该算法基于旋转的Shinnar-Le Roux脉冲设计算法,其中脉冲的频率调制波形由该算法直接设计,其幅度和符号调制波形取代了梯度场。描述了一种新的脉冲配置,该配置能够激发大翻转角切片选择轮廓。进行了实验以验证这些脉冲,并进行了模拟以表征脉冲对失谐的敏感性,并将它们与绝热(BIR-4)脉冲进行比较。