Ito M, Hara K, Saga S, Asai J, Iijima S
1st. Department of Pathology, Nagoya University School of Medicine, Japan.
Acta Pathol Jpn. 1988 Dec;38(12):1565-73. doi: 10.1111/j.1440-1827.1988.tb02296.x.
We report two cases of acquired toxoplasmic lymphadenitis, one with toxoplasmic cysts and the organisms of Toxoplasma gondii and the other with the organisms only. These cysts and organisms were observed in paraffin-embedded sections, touch smears and ultrathin sections for electron microscopy. Touch smears were especially valuable for the quick and accurate diagnosis of toxoplasmic lymphadenitis. We also studied immature sinus histiocytosis (ISH) in these cases. The predominant cells of ISH were confirmed to be B lymphocytes immunohistochemically, the majority being positive for polyclonal surface IgM. ISH was observed in the perifollicular and paracortical areas surrounding post-capillary venules (PCV), whereas the sinuses were only partially involved.
我们报告了两例获得性弓形虫淋巴结炎病例，一例有弓形虫囊肿和刚地弓形虫病原体，另一例仅有病原体。这些囊肿和病原体在石蜡包埋切片、触片和用于电子显微镜检查的超薄切片中均有观察到。触片对于快速准确诊断弓形虫淋巴结炎特别有价值。我们还研究了这些病例中的未成熟窦组织细胞增生症（ISH）。免疫组织化学证实ISH的主要细胞为B淋巴细胞，大多数对多克隆表面IgM呈阳性。ISH见于毛细血管后微静脉（PCV）周围的滤泡周和副皮质区，而窦仅部分受累。
