Kraus Gabriel, Fortes Sofia, Vazquez Joyce, Renfree Kevin J
Orthopedics. 2014 Feb;37(2):e214-7. doi: 10.3928/01477447-20140124-29.
Osteoid osteoma is a common benign osteogenic bone neoplasm characterized histologically by increased osteoid tissue formation with an intracortical nidus surrounded by cortical thickening and vascular fibrous stroma and sclerosis. The clinical presentation classically includes severe nocturnal pain that is improved with nonsteroidal anti-inflammatory drugs. Younger men (second and third decades) have the highest incidence, with the most frequent sites of involvement being the long bones or axial skeleton. Osteoid osteoma may be missed due to the lesion occurring in an atypical location or due to failure to obtain advanced imaging studies such as computed tomography (CT). Intralesional or wide excision, or CT-guided radiofrequency ablation if available, leads to predictable and rapid pain relief. The authors report the case of a 24-year-old man who had a painful flexion contracture of his dominant right elbow for 1.5 years, secondary to an intra-articular osteoid osteoma. Attempted motion, passive or active, produced a marked exacerbation of pain. Previous surgeries, including an elbow synovectomy and an ulnar nerve transposition, had been unsuccessful in relieving his pain. Plain radiographs demonstrated a small area of periosteal thickening adjacent to the sublime tubercle. Fine-cut CT scan demonstrated an osteoid osteoma within the articular surface of the trochlear notch of the olecranon, adjacent to the sublime tubercle. Because of a perceived risk to the surrounding articular cartilage, CT-guided radiofrequency ablation was not performed. Wide en bloc surgical excision of the nidus was performed, with complete resolution of pain and rapid return to normal function.
骨样骨瘤是一种常见的良性成骨性骨肿瘤,其组织学特征为骨样组织形成增加,皮质内有瘤巢,周围有皮质增厚、血管纤维性间质和硬化。临床表现通常包括严重的夜间疼痛,使用非甾体类抗炎药可缓解。年轻男性(二三十岁)发病率最高,最常受累部位是长骨或中轴骨骼。骨样骨瘤可能因病变发生在非典型部位或未进行如计算机断层扫描(CT)等先进影像学检查而漏诊。病灶内切除或广泛切除,或在可行时进行CT引导下射频消融,可带来可预测的快速疼痛缓解。作者报告了一例24岁男性病例,其优势右侧肘关节疼痛性屈曲挛缩1.5年,继发于关节内骨样骨瘤。试图进行被动或主动活动时,疼痛会明显加剧。此前包括肘关节滑膜切除术和尺神经移位术在内的手术均未能缓解其疼痛。X线平片显示在小结节附近有一小片骨膜增厚区域。薄层CT扫描显示在尺骨鹰嘴滑车切迹关节面内、靠近小结节处有一个骨样骨瘤。由于担心对周围关节软骨有风险,未进行CT引导下射频消融。对瘤巢进行了广泛整块手术切除,疼痛完全缓解,功能迅速恢复正常。