Experimental, Diagnostic and Specialty Medicine Department, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy.
Experimental, Diagnostic and Specialty Medicine Department, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy.
J Biomech. 2014 May 7;47(7):1618-25. doi: 10.1016/j.jbiomech.2014.03.001. Epub 2014 Mar 12.
Aortic counterpulsation (IABP) consists in an ECG-controlled forced deflation and inflation of a balloon positioned in the aorta. The device is designed to decrease the ventricular afterload during systole and to increase the coronary driving pressure during diastole. In biomechanical terms, the IABP improves the mechanical matching between the pump and the load, facilitating the transfer of ventricular energy. This paper describes a completely passive aortic counterpulsation solution, with an intra-aortic balloon without a pumping system, designed to improve the mechanical matching between the ventricle and the artery at very low cost and complexity. The only requirement is an external reservoir to amplify the balloon pulsations due to physiologic arterial pressure pulse. Using a cardiovascular simulator and changing the reservoir pressure, a systolic not negligible (7.8ml) gas volume exchange between the intra-aortic balloon and the reservoir was measured. The same cardiovascular simulator was used to demonstrate an increase in stroke volume in three conditions of progressive ventricular failure, by detecting a change in systolic and diastolic arterial pressures and stroke volume (SV). The maximal arterial pressure always decreased and the diastolic pressure increased. The SV increased up to 7.8%, demonstrating an arterial elastance reduction and better ventricular-aortic mechanical matching and energy transfer.
主动脉内球囊反搏(IABP)通过在主动脉内定位的球囊进行心电图控制的强制放气和充气。该设备旨在降低收缩期心室后负荷,并在舒张期增加冠状动脉驱动压。从生物力学的角度来看,IABP 改善了泵和负载之间的机械匹配,促进了心室能量的传递。本文描述了一种完全被动的主动脉内球囊反搏解决方案,采用无泵送系统的主动脉内球囊,旨在以非常低的成本和复杂性改善心室和动脉之间的机械匹配。唯一的要求是一个外部储液器,以放大由于生理动脉压力脉冲引起的球囊脉动。使用心血管模拟器并改变储液器压力,测量了主动脉内球囊和储液器之间的不可忽略的(7.8ml)气体体积交换。使用相同的心血管模拟器,通过检测收缩压和舒张压以及每搏量(SV)的变化,在三种逐渐出现心室衰竭的情况下证明了每搏量的增加。最大动脉压始终降低,舒张压升高。SV 增加了 7.8%,表明动脉弹性降低,心室-动脉机械匹配和能量传递更好。