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处方药物滥用的医源性流行:阿片类药物可及性与滥用的县级决定因素

The iatrogenic epidemic of prescription drug abuse: county-level determinants of opioid availability and abuse.

作者信息

Wright Eric R, Kooreman Harold E, Greene Marion S, Chambers R Andrew, Banerjee Aniruddha, Wilson Jeffrey

机构信息

Georgia State University, USA.

Center for Health Policy, Indiana University Richard M. Fairbanks School of Public Health at Indiana University-Purdue University Indianapolis (IUPUI), USA.

出版信息

Drug Alcohol Depend. 2014 May 1;138:209-15. doi: 10.1016/j.drugalcdep.2014.03.002. Epub 2014 Mar 14.

Abstract

BACKGROUND

Opioid use and abuse in the United States continues to expand at an alarming rate. In this study, we examine the county-level determinants of the availability and abuse of prescription opioids to better understand the socio-ecological context, and in particular the role of the healthcare delivery system, on the prescription drug abuse epidemic.

METHODS

We use community-level information, data from Indiana's prescription drug monitoring program in 2011, and geospatial regression methods to identify county-level correlates of the availability and abuse of prescription opioids among Indiana's 92 counties.

RESULTS

The findings suggest that access to healthcare generally, and to dentists and pharmacists in particular, increases the availability of prescription opioids in communities, which, in turn, is associated with higher rates of opioid abuse.

CONCLUSIONS

The results suggest that the structure of the local healthcare system is a major determinant of community-level access to opioids adding to a growing body of evidence that the problem of prescription opioid abuse is, at least in part, an "iatrogenic epidemic."

摘要

背景

美国阿片类药物的使用和滥用现象正以惊人的速度持续蔓延。在本研究中,我们考察了县级层面上处方阿片类药物可得性及滥用的决定因素,以更好地理解社会生态背景,尤其是医疗服务提供系统在处方药滥用流行问题上所起的作用。

方法

我们运用社区层面的信息、2011年印第安纳州处方药监测项目的数据以及地理空间回归方法,来确定印第安纳州92个县中处方阿片类药物可得性及滥用的县级相关因素。

结果

研究结果表明,总体上获得医疗服务,尤其是看牙医和找药剂师,会增加社区中处方阿片类药物的可得性,而这反过来又与更高的阿片类药物滥用率相关。

结论

结果表明,当地医疗系统的结构是社区层面获取阿片类药物的一个主要决定因素,这进一步证明了越来越多的证据所表明的,处方阿片类药物滥用问题至少在一定程度上是一场“医源性流行病”。

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