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[疗养院早期康复阶段缺血性心脏病患者血清中的磷脂]

[Phospholipids in the blood serum of patients with ischemic heart disease at the stage of early rehabilitation at a sanatorium].

作者信息

Novgorodtseva T P, Endakova E A, Ivanov E M, Svetashev V I, Beliaeva N E

出版信息

Lab Delo. 1989(1):15-8.

PMID:2468016
Abstract

Lipid metabolism has been examined in coronary patients from the content of the blood serum phospholipid fractions during exposure to the health resort factors at the South of the Primorye territory. Qualitative composition of phospholipids included 5 fractions, i.e. phosphatidylcholine, sphingomyelin, lysophosphatidylcholine, phosphatidylethanolamine, and phosphatidylinosite. Decreased levels of phosphatidylcholine and elevated concentrations of lysophosphatidylcholine and sphingomyelin have been detected in the patients. No differences in the concentrations of phospholipid fractions in patients with extensive and small-focus myocardial infarctions have been observed. Patients with repeated myocardial infarctions in the history have developed drastic changes in lipid metabolism, i.e. abnormal levels of phosphatidylcholine, lysophosphatidylcholine, and sphingomyelin. Lipid metabolism parameters have not normalized in coronary patients in the course of health resort treatment.

摘要

在滨海边疆区南部疗养因子作用期间,通过检测冠心病患者血清磷脂组分含量来研究脂质代谢。磷脂的定性组成包括5种组分,即磷脂酰胆碱、鞘磷脂、溶血磷脂酰胆碱、磷脂酰乙醇胺和磷脂酰肌醇。已检测到患者体内磷脂酰胆碱水平降低,溶血磷脂酰胆碱和鞘磷脂浓度升高。未观察到大面积和小灶性心肌梗死患者磷脂组分浓度存在差异。有多次心肌梗死病史的患者出现了脂质代谢的剧烈变化,即磷脂酰胆碱、溶血磷脂酰胆碱和鞘磷脂水平异常。在疗养治疗过程中,冠心病患者的脂质代谢参数未恢复正常。

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