Lefere M, Larbi A, Malghem J, Vande Berg B, Dallaudière B
Department of Radiology, University Hospitals Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium,
Skeletal Radiol. 2014 Aug;43(8):1185-90. doi: 10.1007/s00256-014-1870-1. Epub 2014 Mar 29.
Vertebral involvement in sarcoidosis is rare and its clinical and imaging features are non-specific. Indeed, because the lesions are hard to differentiate from metastatic disease based on imaging alone, a histological confirmation is advised. Fatty replacement is a well-known finding indicating stabilization and healing in both benign and malignant conditions. It can be used as an indicator of a favorable disease course and response to treatment. We report the case of a 43-year-old woman with multifocal vertebral sarcoidosis lesions and long-term follow-up showing progressive and gradual fatty involution on magnetic resonance imaging (MRI) during 4 years of steroid treatment with a final favorable outcome.
结节病累及脊柱较为罕见,其临床和影像学特征不具有特异性。实际上,由于仅凭影像学很难将这些病变与转移性疾病区分开来,因此建议进行组织学确诊。脂肪替代是一个众所周知的表现,表明在良性和恶性疾病中病情均已稳定并正在愈合。它可用作疾病进展良好及对治疗有反应的指标。我们报告了一例43岁女性患者,其患有多灶性脊柱结节病病变,长期随访显示,在4年的类固醇治疗期间,磁共振成像(MRI)显示病变逐渐出现脂肪消退,最终预后良好。