Plisson L, Patron V, Luna Azoulay B, Babin E, Hitier M
Rev Laryngol Otol Rhinol (Bord). 2013;134(2):109-12.
Paraganglioma are uncommon neuroendocrine tumours arising from extra-adrenal chromaffin cells of the autonomic nervous system. In the head and neck region, these neoplasms most commonly arise from the carotid body, the vagus nerve, and the jugulotympanic area. We present the case of a 69-year-old woman who suffered from dyspnoea and dysphonia for six months. A biopsy diagnosed a laryngeal haemangioma and a resection of the tumour was performed using supraglottic pharyngolaryngectomy. Definitive histopathological examination revealed a laryngeal paraganglioma. Laryngeal paraganglioma and haemangioma must be evoked when confronted with a submucosal vascular laryngeal tumour. In such cases biopsies should be avoided. Exhaustive imaging is a key factor in the diagnosis and should include an MRI and an arteriography in order to rule out other differential diagnoses. To our knowledge this is the first case focusing on this issue.
副神经节瘤是起源于自主神经系统肾上腺外嗜铬细胞的罕见神经内分泌肿瘤。在头颈部区域,这些肿瘤最常见于颈动脉体、迷走神经和颈鼓区。我们报告一例69岁女性,她有6个月的呼吸困难和声音嘶哑症状。活检诊断为喉血管瘤,并采用声门上型咽喉切除术切除肿瘤。最终的组织病理学检查显示为喉副神经节瘤。当面对黏膜下血管性喉部肿瘤时,必须考虑喉副神经节瘤和血管瘤。在这种情况下应避免活检。详尽的影像学检查是诊断的关键因素,应包括磁共振成像(MRI)和动脉造影,以排除其他鉴别诊断。据我们所知,这是首例关注此问题的病例。