Pham T A, De Freitas R, Young G, Safdar A
Department of Otorhinolaryngology, Head and Neck Surgery, Monash Medical Centre, Victoria, Australia.
J Laryngol Otol. 2012 Jul;126(7):747-50. doi: 10.1017/S0022215112000849. Epub 2012 May 29.
We present the first reported case of a paraganglioma of the larynx occurring concurrently with squamous cell carcinoma in an irradiated neck.
We present a case report and a literature review of paraganglioma of the larynx.
A 78-year-old woman was found to have a mass on the laryngeal surface of the epiglottis and non-functioning larynx, four months after radical radiotherapy for biopsy-proven squamous cell carcinoma. Repeated positron emission tomography computed tomography was highly suggestive of residual malignancy. Given these findings, and the fact that the patient was aspirating, she was treated with total laryngectomy, and was found to have a paraganglioma of the larynx.
This is the first report of such a case. Its importance is three-fold in that it demonstrates: the coexistence of paraganglioma and squamous cell carcinoma; the difficulties that can be encountered in the diagnosis; and the use of radiotherapy in the treatment of paraganglioma.
我们报告首例喉副神经节瘤与放疗后颈部鳞状细胞癌同时发生的病例。
我们呈现一例喉副神经节瘤的病例报告及文献综述。
一名78岁女性在经活检证实为鳞状细胞癌的根治性放疗四个月后,被发现会厌喉面有肿物且喉部无功能。重复的正电子发射断层扫描计算机断层扫描高度提示残留恶性肿瘤。鉴于这些发现以及患者存在误吸情况,她接受了全喉切除术,术中发现患有喉副神经节瘤。
这是此类病例的首例报告。其重要性体现在三个方面,即它证明了:副神经节瘤与鳞状细胞癌并存;诊断中可能遇到的困难;以及放疗在副神经节瘤治疗中的应用。