Busin V, Kenyon F, Parkin T, McBean D, Laing N, Sargison N D, Ellis K
Scottish Centre for Production Animal Health and Food Safety, School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ, UK.
Vet J. 2014 May;200(2):248-52. doi: 10.1016/j.tvjl.2014.02.012. Epub 2014 Feb 28.
The sustainability of sheep production is hindered by anthelmintic resistance. Options to slow down or prevent resistance have been widely studied but their application in the field is still limited. In this study, the practical application and effect of a targeted selective treatment (TST) approach for the treatment of parasitic gastroenteritis was investigated in lambs (n = 385) over a 2 year period. At 14-day intervals during the grazing season, liveweight, breech soiling and anthelmintic treatments were individually recorded. Selection of lambs for anthelmintic treatment in the TST group was based on pre-calculated individual growth rates, with a matched cohort routinely treated (RT) with anthelmintic drug every 6 weeks. The adoption of a TST approach had no negative effect on the liveweight gains of the lambs, time to finishing or breech soiling measures compared to RT lambs; however a 50% decrease in anthelmintic treatment was observed in the TST group. The time to implement this system averaged 2 min per lamb. It is concluded that the TST could be suitable for commercial sheep farms, in association with automated weighing systems, potentially reducing selection for anthelmintic resistance, while having no negative effect on production.
抗蠕虫药耐药性阻碍了绵羊生产的可持续性。减缓或预防耐药性的方法已得到广泛研究，但它们在实际中的应用仍然有限。在本研究中，对385只羔羊在两年时间内采用针对性选择性治疗（TST）方法治疗寄生性胃肠炎的实际应用及效果进行了调查。在放牧季节，每隔14天分别记录羔羊的体重、臀部污染情况及抗蠕虫药治疗情况。TST组中选择接受抗蠕虫药治疗的羔羊是基于预先计算的个体生长率，同时设立一个匹配队列，每6周常规使用抗蠕虫药进行治疗（RT）。与RT组羔羊相比，采用TST方法对羔羊的体重增加、育肥时间或臀部污染情况均无负面影响；然而，TST组的抗蠕虫药治疗次数减少了50%。实施该系统的时间平均每只羔羊为2分钟。得出的结论是，TST方法与自动称重系统相结合，可能适用于商业化养羊场，既能减少对抗蠕虫药耐药性的选择，又对生产没有负面影响。
