Suppr超能文献

肾上腺偶发瘤:英国地区综合医院的管理

Adrenal incidentalomas: management in British district general hospitals.

作者信息

Davenport Emily, Lang Ping Nam Pitsien, Wilson Michael, Reid Alastair, Aspinall Sebastian

机构信息

Department of Surgery, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Trust, Newcastle, UK.

Department of Accident and Emergency, Wansbeck General Hospital, Northumbria Healthcare NHS Trust, Newcastle, UK.

出版信息

Postgrad Med J. 2014 Jul;90(1065):365-9. doi: 10.1136/postgradmedj-2013-132386. Epub 2014 Mar 31.

Abstract

INTRODUCTION

Adrenal incidentalomas have become a common clinical dilemma with the increasing use and resolution of cross sectional imaging modalities.

OBJECTIVES

This retrospective observational study examined the management of adrenal incidentalomas in district general hospitals in Northumbria and adherence to current guidelines.

MATERIALS AND METHODS

We searched 4028 abdominal CT scans performed in Northumbria between 1 January and 31 December 2010. All patients with an incidental adrenal lesion were identified and their clinical records reviewed.

RESULTS

75 patients with adrenal incidentalomas were identified. Of these, only 13 (17%) were referred for specialist review with a further two patients undergoing additional evaluation by the primary medical team; 80% received no biochemical investigation or follow-up. Comorbidity may have affected the decision in a proportion, but 36 of 62 patients (58%) had no comorbidities precluding additional evaluation. In contrast, all patients reviewed by an endocrine specialist were appropriately investigated and managed, the majority conservatively, with three requiring adrenalectomy for phaeochromocytoma or cortisol secreting adenomas. In the patients with an incidentaloma, comorbidities which may be attributable to autonomous adrenal cortisol or aldosterone release were higher than regional averages, suggesting possible undiagnosed functional tumours.

CONCLUSIONS

The management of adrenal incidentalomas in British district general hospitals in Northumbria shows poor adherence to guidelines. Adherence was significantly better in those patients managed by an endocrine specialist. We suggest a pathway for the management and referral process.

摘要

引言

随着横断面成像技术的广泛应用和分辨率提高,肾上腺偶发瘤已成为常见的临床难题。

目的

本回顾性观察研究旨在探讨诺森伯兰地区综合医院肾上腺偶发瘤的管理情况以及对现行指南的遵循情况。

材料与方法

我们检索了2010年1月1日至12月31日在诺森伯兰进行的4028例腹部CT扫描。识别出所有有肾上腺偶发病变的患者,并查阅其临床记录。

结果

共识别出75例肾上腺偶发瘤患者。其中,只有13例(17%)被转诊至专科医生处进行评估,另有2例患者由初级医疗团队进行了进一步评估;80%的患者未接受生化检查或随访。合并症可能在一定程度上影响了决策,但62例患者中有36例(58%)没有合并症妨碍进一步评估。相比之下,所有经内分泌专科医生评估的患者均得到了适当的检查和管理,大多数采用保守治疗,3例因嗜铬细胞瘤或分泌皮质醇的腺瘤需要进行肾上腺切除术。在偶发瘤患者中,可能归因于自主性肾上腺皮质醇或醛固酮分泌的合并症高于地区平均水平,提示可能存在未诊断的功能性肿瘤。

结论

诺森伯兰地区英国综合医院对肾上腺偶发瘤的管理显示出对指南的遵循情况较差。由内分泌专科医生管理的患者遵循情况明显更好。我们提出了一个管理和转诊流程的路径。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验