Maeda Eri, Ishihara Osamu, Saito Hidekazu, Kuwahara Akira, Toyokawa Satoshi, Kobayashi Yasuki
Department of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
J Obstet Gynaecol Res. 2014 May;40(5):1338-44. doi: 10.1111/jog.12337. Epub 2014 Apr 2.
The aim of this study was to calculate and assess the cost of assisted reproductive technology (ART) treatment cycles and live-birth events in Japan in 2010.
We performed a retrospective analysis of 238,185 ART cycles, registered with the national registry of assisted reproductive treatment during 2010. Costs were calculated, using a decision analysis model.
The average cost per live birth was ¥1,974,000. This varied from ¥1,155,000 in women aged < 30 years to ¥50,189,000 in women aged ≥ 45, which was 29.6 times higher than that of women aged 35-39 years. This rose sharply in the early 40s and upwards. Public funding per live birth was ¥442,000. This was ¥6,118,000 in women aged ≥ 45, 15.4 times higher than that of the 35-39-year-old age group.
The costs and public funding of a live birth after ART treatment rises with age due to the lower success rates in older women. It may provide economic background to improve the current subsidy system for ART and to provide practical knowledge about fertility for the general population.
本研究旨在计算和评估2010年日本辅助生殖技术（ART）治疗周期及活产事件的成本。
我们对2010年期间在国家辅助生殖治疗登记处登记的238,185个ART周期进行了回顾性分析。使用决策分析模型计算成本。
每次活产的平均成本为197.4万日元。这一成本在年龄小于30岁的女性中为115.5万日元，而在年龄≥45岁的女性中则高达5018.9万日元，是35 - 39岁女性成本的29.6倍。在40岁出头及以上年龄段成本急剧上升。每次活产的公共资金为44.2万日元。在年龄≥45岁的女性中，这一数字为611.8万日元，是35 - 39岁年龄组的15.4倍。
由于老年女性成功率较低，ART治疗后活产的成本和公共资金随年龄增长而增加。这可能为改进当前ART补贴系统提供经济背景，并为普通人群提供有关生育的实用知识。
