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用于重建晶状体梯度折射率分布的可调内部结构。

Adjustable internal structure for reconstructing gradient index profile of crystalline lens.

作者信息

Bahrami Mehdi, Goncharov Alexander V, Pierscionek Barbara K

出版信息

Opt Lett. 2014 Mar 1;39(5):1310-3. doi: 10.1364/OL.39.001310.

Abstract

Employing advanced technologies in studying the crystalline lens of the eye has improved our understanding of the refractive index gradient of the lens. Reconstructing and studying such a complex structure requires models with adaptable internal geometry that can be altered to simulate geometrical and optical changes of the lens with aging. In this Letter, we introduce an optically well-defined, geometrical structure for modeling the gradient refractive index profile of the crystalline lens with the advantage of an adjustable internal structure that is not available with existing models. The refractive index profile assigned to this rotationally symmetric geometry is calculated numerically, yet it is shown that this does not limit the model. The study provides a basis for developing lens models with sophisticated external and internal structures without the need for analytical solutions to calculate refractive index profiles.

摘要

在研究眼睛的晶状体时采用先进技术,增进了我们对晶状体折射率梯度的理解。重建和研究这样一个复杂结构需要具有可适应内部几何形状的模型,该模型可以改变以模拟晶状体随年龄增长的几何和光学变化。在本信函中,我们引入了一种光学定义明确的几何结构,用于对晶状体的梯度折射率分布进行建模,其优点是具有可调节的内部结构,这是现有模型所不具备的。分配给这种旋转对称几何形状的折射率分布是通过数值计算得出的,但结果表明这并不限制该模型。该研究为开发具有复杂外部和内部结构的晶状体模型提供了基础,而无需解析解来计算折射率分布。

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