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内侧颞叶脑室外神经细胞瘤:难治性复杂部分性癫痫的罕见病因。

Mesial temporal extraventricular neurocytoma: a rare cause of refractory complex partial seizure.

作者信息

Feng Rui, Hu Jie, Wu Jinsong, Lang Liqin, Wang Bei, Bi Haixia, Gu Xin, Guo Jun, Pan Li

机构信息

Department of Neurosurgery, Huashan Hospital.

Department of Neurosurgery, Huashan Hospital, Department of Neurosurgery, Jing'an Branch of Huashan Hospital.

出版信息

Epileptic Disord. 2014 Mar;16(1):125-31. doi: 10.1684/epd.2014.0633.

Abstract

AIM

Mesial temporal extraventricular neurocytoma (mtEVN) is a rare cause of refractory complex focal seizures. The characteristics of this clinical entity are discussed in this article.

METHODS

We report two cases of mtEVN and review the related literature, with particular emphasis on radiological characteristics, clinical features, and operative techniques.

RESULTS

After successful surgery, our two cases of mtEVN achieved excellent outcome. Including the cases presented here, a total of three cases of mtEVNs and 11 of neocortical temporal extraventricular neurocytoma (ntEVNs) are reported in the literature. mtEVNs are distinct from ntEVNs with regards to demographics, aetiology, radiological features, and operative techniques.

CONCLUSION

mtEVNs and ntEVNs exhibit distinguishing features. Under electrocorticographic monitoring, tailored resection of the neocortical epileptogenic focus, as well as the entire tumour and mesial temporal structures, can yield excellent outcome and satisfactory seizure control.

摘要

目的

内侧颞叶脑室外神经细胞瘤(mtEVN)是难治性复杂局灶性癫痫发作的罕见病因。本文讨论了这一临床实体的特征。

方法

我们报告了两例mtEVN病例,并回顾了相关文献,特别强调了放射学特征、临床特征和手术技术。

结果

成功手术后,我们的两例mtEVN病例取得了良好的效果。包括本文所呈现的病例在内,文献中共报道了3例mtEVN和11例新皮质颞叶脑室外神经细胞瘤(ntEVN)。mtEVN在人口统计学、病因、放射学特征和手术技术方面与ntEVN不同。

结论

mtEVN和ntEVN表现出不同的特征。在皮质电图监测下,对新皮质致痫灶以及整个肿瘤和内侧颞叶结构进行针对性切除,可取得良好效果并实现满意的癫痫控制。

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