Goussot J F, Coindre J M, Merlio J P, de Mascarel A
Department of Pathology, Hôpital, Saint-André, Bordeaux, France.
Tumori. 1989 Feb 28;75(1):79-81. doi: 10.1177/030089168907500121.
A case of atypical fibromyxoid tumor of the urinary bladder in a 32-year-old woman is reported. The patient had never complained of urinary symptoms, and bladder tumefaction was revealed fortuitously at pelvic ultrasound. Cystoscopy revealed a peanut-sized mass. Microscopically, the lesion was composed of strap- and tadpole-shaped cells resembling rhabdomyoblasts. For this reason, the tumor was initially diagnosed as embryonal rhabdomyosarcoma. However, immuno-histochemical study was negative for muscle origin, and the tumor has subsequently proved benign. The reported case illustrates the value of immuno-histochemical study in the evaluation of the true type of bizarre stroma cells in this pseudo-sarcomatous lesion. Their recognition is important, because the therapeutic consequences of misinterpreting this tumor as a sarcoma are great.
报告了一例32岁女性膀胱非典型纤维黏液样肿瘤。患者从未诉说过泌尿系统症状，盆腔超声检查偶然发现膀胱肿物。膀胱镜检查发现一个花生大小的肿块。显微镜下，病变由类似横纹肌母细胞的带状和蝌蚪状细胞组成。因此，该肿瘤最初被诊断为胚胎性横纹肌肉瘤。然而，免疫组织化学研究显示肌肉来源为阴性，随后证实该肿瘤为良性。该报告病例说明了免疫组织化学研究在评估这种假肉瘤性病变中奇异间质细胞真实类型的价值。它们的识别很重要，因为将这种肿瘤误判为肉瘤的治疗后果很严重。
