Habeler W, Ghaleh B, Barthelemy I, Plancheron A, Bizé A, Carlos-Sampedrano C, Chetboul V, Berdeaux A, Pucéat M, Peschanski M, Blot S, Monville C
CECS, I-Stem, AFM , Evry 91030 cedex, France.
INSERM, U955, Créteil , 94000, France ; Université Paris Est, Faculté de médecine, Créteil and Ecole Nationale Vétérinaire d'Alfort , 94000, France.
J Stem Cells Regen Med. 2011 Oct 30;7(2):80-6. doi: 10.46582/jsrm.0702013. eCollection 2011.
Duchenne muscular dystrophy is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Spontaneous canine muscular disorders are interesting settings to evaluate the relevance of innovative therapies in human using pre-clinical trials.
杜氏肌营养不良症的特征是进行性肌肉无力以及由于肌营养不良蛋白缺乏导致的早逝。自发性犬类肌肉疾病是利用临床前试验评估创新疗法在人类中的相关性的有趣研究对象。