Cherix Stéphane, Varelas Nikolaos, Letovanec Igor, Becce Fabio, Gay Béatrice, Matter Maurice, Gonzalez Michel, Saucy François, Christen Thierry, Rüdiger Hannes A
Rev Med Suisse. 2013 Dec 18;9(411):2385-9.
Management of musculoskeletal tumours usually begins with the appearance of a lump or bump, or the onset of unspecific symptoms. A poor initial work-up, a faulty biopsy or an inadequate resection may have a severe impact on the prognosis, including re-interventions, amputation, local recurrence or systemic spread of the disease. The patient with a suspicious lesion should be referred to a "sarcoma centers" where a planned and well-performed diagnostic work-up will allow a precise diagnosis in terms of histology and staging. After a multidisciplinary discussion of the case, an accurate treatment plan is established. Such an approach allows an adequate patient management, often with a positive impact on the survival and functional outcome.
肌肉骨骼肿瘤的管理通常始于肿块或隆起的出现,或非特异性症状的发作。初始检查不完善、活检有误或切除不充分可能会对预后产生严重影响,包括再次干预、截肢、局部复发或疾病的全身扩散。有可疑病变的患者应转诊至“肉瘤中心”,在那里进行有计划且执行良好的诊断检查将能在组织学和分期方面做出精确诊断。在对病例进行多学科讨论后,制定准确的治疗计划。这种方法能实现对患者的充分管理,通常对生存和功能结局有积极影响。