新生仔猪中识别共有的革兰氏阴性核心抗原的被动获得性免疫球蛋白的优先衰减
Preferential decay of passively acquired immunoglobulins recognizing shared gram-negative core antigens in neonatal swine.
作者信息
Tyler J W, Cullor J S, Douglas V L, Smith W L, Parker K M
机构信息
Department of Clinical Pathology, School of Veterinary Medicine University of California, Davis 95616.
出版信息
Am J Vet Res. 1989 Apr;50(4):480-2.
Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured by use of a direct ELISA on blood obtained from 10 neonatal swine. An R-mutant Escherichia coli (strain J5) was used as a plate antigen. Total serum IgG was measured by use of radial immunodiffusion. Half-lives of core antigen-specific IgG (6.81 days) and total serum IgG (14.85 days) were dramatically different (P less than 0.01).
通过直接酶联免疫吸附测定法（ELISA），连续检测了10头新生仔猪血液中识别常见革兰氏阴性菌细胞核心表位的IgG同种型血清免疫球蛋白。以R突变型大肠杆菌（菌株J5）作为包被抗原。采用放射免疫扩散法测定血清总IgG。核心抗原特异性IgG（6.81天）和血清总IgG（14.85天）的半衰期差异显著（P<0.01）。
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