Rohenkohl A C, De Schepper J, Vanderfaeillie J, Fricke K, Hendrickx S, Lagrou K, Bullinger M, Quitmann J
Acta Clin Belg. 2014 Jun;69(3):177-82. doi: 10.1179/2295333714Y.0000000024. Epub 2014 Apr 2.
The Quality of Life in Short Stature Youth (QoLISSY) questionnaire was recently developed in five European countries to assess health-related quality of life in children and adolescents with idiopathic short stature or growth hormone deficiency from child and parent perspectives. In addition to the existing French version, a Flemish version is needed for use of QoLISSY in the Flemish speaking part of Belgium.
Children (8-18 years) and their parents recruited from two Belgian paediatric endocrinology clinics completed the QoLISSY in a cross-sectional study. Cronbach's Alpha and test-retest reliability was assessed. Validity was examined by correlation with the generic KIDSCREEN questionnaire as well as by group comparisons according to diagnostic and treatment status.
The QoLISSY scales had an acceptable internal consistency with Cronbach's Alpha ranging from 0·80 to 0·94 (child version) and from 0·77 to 0·92 (parent version). Test-retest reliability correlation coefficients ranged from r = 0·75 to 0·89 in the child version and from r = 0·58 to 0·85 in the parent version. Moderate correlations with the generic KIDSCREEN questionnaire suggested construct validity. Differences between child groups according to child age, underlying diagnosis, and degree of height deficit were found. Correlations with the European QoLISSY were significant for all scales.
The Flemish QoLISSY instrument is a psychometrically sound, reliable, and valid short stature specific questionnaire measuring health-related quality of life. It is expected to be of great use in upcoming clinical research on growth disorders and growth hormone treatment in Belgium and Europe.
近期在五个欧洲国家开发了矮小青年生活质量(QoLISSY)问卷,以从儿童和家长的角度评估特发性矮小或生长激素缺乏的儿童及青少年与健康相关的生活质量。除了现有的法语版本外,还需要一个弗拉芒语版本以便在比利时讲弗拉芒语的地区使用QoLISSY。
从两家比利时儿科内分泌诊所招募的儿童(8 - 18岁)及其父母在一项横断面研究中完成了QoLISSY问卷。评估了克朗巴哈系数(Cronbach's Alpha)和重测信度。通过与通用的儿童生活质量问卷(KIDSCREEN)的相关性以及根据诊断和治疗状况进行组间比较来检验效度。
QoLISSY量表具有可接受的内部一致性,克朗巴哈系数在儿童版中为0.80至0.94,在家长版中为0.77至0.92。儿童版的重测信度相关系数范围为r = 0.75至0.89,家长版为r = 0.58至0.85。与通用的KIDSCREEN问卷的中度相关性表明了结构效度。发现根据儿童年龄、潜在诊断和身高缺陷程度划分的儿童组之间存在差异。所有量表与欧洲QoLISSY的相关性均显著。
弗拉芒语QoLISSY工具是一种心理测量学上合理、可靠且有效的特定于矮小症的问卷,用于测量与健康相关的生活质量。预计它将在比利时和欧洲即将开展的关于生长障碍和生长激素治疗的临床研究中发挥重要作用。