Clemence Bonnie J, Maneval Rhonda E
PinnacleHealth System, Harrisburg, Pennsylvania (Ms Clemence and Dr Maneval); and Temple University, Philadelphia, Pennsylvania (Dr Maneval). Bonnie J. Clemence, MSN, RN, CRNI®, was a staff nurse in the IV therapy department at PinnacleHealth System in Harrisburg, Pennsylvania. She has extensive experience as an infusion therapy and pediatric nurse. Rhonda E. Maneval, DEd, MSN, RN, is a professor of nursing and associate chair for undergraduate nursing education at Temple University in Philadelphia. She is also a nursing research consultant for PinnacleHealth System.
J Infus Nurs. 2014 May-Jun;37(3):187-96. doi: 10.1097/NAN.0000000000000037.
This is part 1 of a 2-part series of articles that report on the results of a prospective observational cohort study designed to examine the risk factors associated with symptomatic upper extremity deep vein thrombosis (UEDVT) in patients with peripherally inserted central catheters. This article provides an extensive review and critique of the literature that serves to explicate what is currently known about risk factors associated with catheter-related UEDVT. Risk factors such as anticoagulant use, cancer, infection, hypertension, catheter tip placement, and catheter size were identified most frequently in the literature as being associated with UEDVT development. Other risk factors--such as obesity, smoking history, surgery, and presence of pain or edema--were examined in a limited number of studies and lacked consistent evidence of their impact on UEDVT development. The subsequent study that evolved from the review of the literature investigates the relationship between identified risk factors and UEDVT development.
这是一篇分两部分的系列文章中的第1部分，该系列报道了一项前瞻性观察队列研究的结果，该研究旨在检查外周静脉置入中心静脉导管患者出现症状性上肢深静脉血栓形成（UEDVT）的相关危险因素。本文对相关文献进行了广泛回顾和评论，以阐明目前已知的与导管相关UEDVT的危险因素。文献中最常确定的危险因素包括抗凝剂使用、癌症、感染、高血压、导管尖端位置和导管尺寸，这些都与UEDVT的发生有关。其他危险因素，如肥胖、吸烟史、手术以及疼痛或水肿的存在，在少数研究中进行了检查，且缺乏关于其对UEDVT发生影响的一致证据。基于文献综述开展的后续研究调查了已确定的危险因素与UEDVT发生之间的关系。
