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[急性胰腺炎与疾病早期的红细胞分布宽度(RDW)]

[Acute pancreatitis and red cell distribution width (RDW)I at early phase of disease].

作者信息

Kolber Witold, Sporek Mateusz, Dumnicka Paulina, Kuśnierz-Cabala Beata, Kuzniewski Marek, Gurda-Duda Anna, Solnica Bogdan, Kulig Jan

出版信息

Przegl Lek. 2013;70(11):916-9.

Abstract

During last decade, many new biomarkers have been proposed for early diagnosis of acute pancreatitis and prognosis of its severity. However clinical availability of many markers are limited due to costly and time. consuming laboratory methods used, for their assessment, including ELISA technique. Recent studies revealed the usefulness of red cell distribution width (RDW), as a predictor of unfa vorable prognosis in many disease states. RDW is an easily available index generated automatically as a part of standard complete blood count In our group of 40 acute pancreatitis patients, RDW values assessed du ring first 5 days of disease, correlated positively with the duration of hospital stay and the severity of disease as well as with the concentration of selected inflammatory markers. Patients who died had significantly higher RDW comparing to survivors. Our results indicate that RDW may be helpful in early prediction of clinical course of acute pancreatitis.

摘要

在过去十年中,人们提出了许多新的生物标志物用于急性胰腺炎的早期诊断及其严重程度的预后评估。然而,由于评估这些标志物所使用的实验室方法成本高且耗时,包括酶联免疫吸附测定(ELISA)技术,许多标志物的临床实用性有限。最近的研究表明,红细胞分布宽度(RDW)作为许多疾病状态下不良预后的预测指标具有实用性。RDW是作为标准全血细胞计数的一部分自动生成的易于获得的指标。在我们的40例急性胰腺炎患者组中,在疾病的前5天评估的RDW值与住院时间、疾病严重程度以及所选炎症标志物的浓度呈正相关。死亡患者的RDW显著高于幸存者。我们的结果表明,RDW可能有助于急性胰腺炎临床病程的早期预测。

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