红细胞分布宽度作为急性胰腺炎患者死亡率的预测指标。
Red cell distribution width as a predictor of mortality in acute pancreatitis.
机构信息
Department of Surgery, Ankara Numune Training and Research Hospital, Bahçelievler, Ankara, Turkey.
出版信息
Am J Emerg Med. 2013 Apr;31(4):687-9. doi: 10.1016/j.ajem.2012.12.015. Epub 2013 Feb 8.
INTRODUCTION
Acute pancreatitis (AP) is a common cause for hospitalization worldwide. Identification of patients at risk for mortality early in the course of AP is an important step in improving outcome. Red cell distribution width (RDW) is reflective of systemic inflammation. The objective of this study was to investigate the association between RDW and mortality in patients with AP.
METHODS
A total of 102 patients with AP were included. Demographic data, etiology of pancreatitis, organ failure, metabolic disorder, hospitalization time, and laboratory measures including RDW were obtained from each patient on admission.
RESULTS
Estimating the receiver operating characteristic area under the curve showed that RDW has very good discriminative power for mortality (area under the curve = 0.817; 95% confidence interval, 0.689-0.946). With a cutoff value of 14.8 for RDW, mortality could be correctly predicted in approximately 77% of cases.
CONCLUSIONS
Red cell distribution width on admission is a predictor of mortality in patients with AP.
简介
急性胰腺炎（AP）是全球范围内常见的住院原因。在 AP 病程早期识别有死亡风险的患者是改善预后的重要步骤。红细胞分布宽度（RDW）反映全身炎症。本研究旨在探讨 RDW 与 AP 患者死亡率之间的关系。
方法
共纳入 102 例 AP 患者。每位患者入院时均获取人口统计学数据、胰腺炎病因、器官衰竭、代谢紊乱、住院时间和实验室指标，包括 RDW。
结果
估算受试者工作特征曲线下面积表明，RDW 对死亡率具有很好的区分能力（曲线下面积=0.817；95%置信区间，0.689-0.946）。RDW 的截断值为 14.8 时，约 77%的病例可以正确预测死亡率。
结论
入院时的 RDW 是 AP 患者死亡率的预测指标。
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