Stafford N D, Herdman R C, Forster S, Munro A J
Department of ENT Surgery, St. Mary's Hospital, London.
J Laryngol Otol. 1989 Apr;103(4):379-82. doi: 10.1017/s0022215100109016.
Over a 40 month period, 219 patients with AIDS were seen at St. Mary's Hospital, London. Kaposi's sarcoma, one of the criteria for diagnosing the syndrome, was the presenting feature in 62 patients. Eighty four patients developed Kaposi's sarcoma at some stage of their disease and the head and neck region was involved in 56 of them. Although Kaposi's sarcoma is rarely life threatening in AIDS, potential airway obstruction, pain or cosmetic disfigurement may justify treating the lesion. Whilst cutaneous tumours may be managed by using radiotherapy (16 Gray in four fractions over four days), this treatment produces a sever mucositis when used to treat mucosal disease; we, therefore use a combination of vincristine and bleomycin for this.
在40个月的时间里，伦敦圣玛丽医院共接诊了219例艾滋病患者。卡波西肉瘤是诊断该综合征的标准之一，62例患者以其为首发症状。84例患者在病程的某个阶段出现了卡波西肉瘤，其中56例累及头颈部区域。尽管卡波西肉瘤在艾滋病中很少危及生命，但潜在的气道阻塞、疼痛或外观损毁可能使治疗该病变具有合理性。虽然皮肤肿瘤可通过放疗治疗（4天内分4次给予16格雷剂量），但这种治疗用于治疗黏膜疾病时会产生严重的黏膜炎；因此，我们为此使用长春新碱和博来霉素联合治疗。
