Prasad Charushree, Corbett Bradley A, Prasad Asuri N
Western University, Canada; Schulich School of Medicine and Dentistry, Canada.
Western University, Canada; Ivey School of Business at Western University, Canada.
Seizure. 2014 Jun;23(6):435-8. doi: 10.1016/j.seizure.2014.03.001. Epub 2014 Mar 13.
Utilizing data from the National Longitudinal Survey of Children and Youth (NLSCY) we evaluated the association between childhood epilepsy and health impairments on measures of school readiness employed in the survey.
Standard scores on the Peabody Picture Vocabulary Test-Revised (PPVT-R) were employed in a regression analysis to compare scores in children with and without epilepsy. We also examined the effect of impairments in any of the 8 domains of the Health Utilities index (HUI) on test scores.
A total sample size of 39,130 children (20,044 males, and 19,086 female were included in the analysis, 33,560 children were administered the PPVT-R at a mean age of 4.5 years. There were 70 children with epilepsy, 21 had a score of 1 on the HUI, 21 were assessed to have a HUI<1 (signifying health impairments in one or more of the 8 domains). In the remainder, the PPVT scores were missing. Using the Ordinary Least Squares (OLS) regression for continuous outcomes model for PPVT-R scores as the outcome variable, females scored 1.1 points higher (β=1.1, 95% CI 0.755, 1.444, p=0.000), children without epilepsy and HUI score of <1 scored 3.84 points lower (β = -3.843 95% CI -4.232, -3.452, p=0.000). Children with epilepsy and a HUI score of 1 scored 9.90 points lower (β = -9.902, 95% CI -16.343, -3.461, p=0.003) while those with epilepsy and HUI<1 scored 17.30 lower (β = -17.308, 95%CI -23.776, -10.839, p=0.000).
The data provide objective evidence that children with epilepsy are at risk of scholastic underachievement at school entry, while those with additional health impairments as measured by the HUI are at greater risk of underachievement.
利用全国儿童和青少年纵向调查（NLSCY）的数据，我们在该调查所采用的入学准备措施方面评估了儿童癫痫与健康损害之间的关联。
在回归分析中采用皮博迪图片词汇测验修订版（PPVT-R）的标准分数来比较有癫痫和无癫痫儿童的分数。我们还研究了健康效用指数（HUI）8个领域中任何一个领域的损害对测验分数的影响。
分析纳入了总共39130名儿童（20044名男性和19086名女性），33560名儿童在平均年龄4.5岁时接受了PPVT-R测试。有70名癫痫儿童，21名HUI评分为1，21名被评估为HUI<1（表示在8个领域中的一个或多个领域存在健康损害）。其余儿童的PPVT分数缺失。以PPVT-R分数作为结果变量，使用连续结果模型的普通最小二乘法（OLS）回归，女性得分高1.1分（β = 1.1，95%可信区间0.755，1.444，p = 0.000），无癫痫且HUI得分<1的儿童得分低3.84分（β = -3.843，95%可信区间-4.232，-3.452，p = 0.000）。癫痫且HUI得分为1的儿童得分低9.90分（β = -9.902，95%可信区间-16.343，-3.461，p = 0.003），而癫痫且HUI<1的儿童得分低17.30分（β = -17.308，95%可信区间-23.776，-10.839，p = 0.000）。
数据提供了客观证据，表明癫痫儿童在入学时存在学业成绩不佳的风险，而那些经HUI测量有额外健康损害的儿童学业成绩不佳的风险更大。
