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Potentially large yet uncertain benefits: a meta-analysis of patent foramen ovale closure trials.潜在的巨大但不确定的益处:卵圆孔未闭封堵试验的荟萃分析。
Stroke. 2013 Sep;44(9):2640-3. doi: 10.1161/STROKEAHA.113.001773. Epub 2013 Jul 18.
2
Cervical artery dissection: trauma and other potential mechanical trigger events.颈内动脉夹层:创伤和其他潜在的机械触发事件。
Neurology. 2013 May 21;80(21):1950-7. doi: 10.1212/WNL.0b013e318293e2eb. Epub 2013 May 1.
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Differences and similarities between spontaneous dissections of the internal carotid artery and the vertebral artery.颈内动脉和椎动脉自发性夹层的差异与相似之处。
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Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.卵圆孔未闭封堵与隐源性卒中后药物治疗的比较。
N Engl J Med. 2013 Mar 21;368(12):1092-100. doi: 10.1056/NEJMoa1301440.
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Percutaneous closure of patent foramen ovale in cryptogenic embolism.经皮卵圆孔未闭封堵术治疗隐源性栓塞。
N Engl J Med. 2013 Mar 21;368(12):1083-91. doi: 10.1056/NEJMoa1211716.
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Long-term mortality after stroke among adults aged 18 to 50 years.18 至 50 岁成年人卒中后的长期死亡率。
JAMA. 2013 Mar 20;309(11):1136-44. doi: 10.1001/jama.2013.842.
7
Ischemic stroke and transient ischemic attack in young adults: risk factors, diagnostic yield, neuroimaging, and thrombolysis.年轻人的缺血性卒中和短暂性脑缺血发作:危险因素、诊断率、神经影像学和溶栓治疗。
JAMA Neurol. 2013 Jan;70(1):51-7. doi: 10.1001/jamaneurol.2013.575.
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Age at stroke: temporal trends in stroke incidence in a large, biracial population.发病年龄:大型、多种族人群中风发病率的时间趋势。
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Antiplatelets vs anticoagulation for dissection: CADISS nonrandomized arm and meta-analysis.抗血小板与抗凝治疗夹层:CADISS 非随机分组研究及其荟萃分析。
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10
Thrombolysis in cervical artery dissection--data from the Cervical Artery Dissection and Ischaemic Stroke Patients (CADISP) database.颈内动脉夹层溶栓治疗——来自颈内动脉夹层和缺血性卒中患者(CADISP)数据库的数据。
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青年成人卒中的评估与管理

Evaluation and management of stroke in young adults.

作者信息

Mackey Jason

出版信息

Continuum (Minneap Minn). 2014 Apr;20(2 Cerebrovascular Disease):352-69. doi: 10.1212/01.CON.0000446106.74796.e9.

DOI:10.1212/01.CON.0000446106.74796.e9
PMID:24699486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10563902/
Abstract

PURPOSE OF REVIEW

This article provides an overview of the evaluation and management of ischemic stroke in young adults, with an emphasis on cervical artery dissection, patent foramen ovale, and hypercoagulable states.

RECENT FINDINGS

The incidence of ischemic stroke in young patients is increasing, although the reasons remain unclear. Patients with ischemic stroke at a young age are more likely to die at an early age than their peers. Well-established vascular risk factors are prevalent in young stroke patients. Recent studies have informed the treatment of dissection and patent foramen ovale among others. The utility of testing for hypercoagulable states in ischemic stroke is unclear.

SUMMARY

Ischemic stroke in young adults is a major public health problem. A wide range of etiologies of ischemic stroke is found in this age group. A careful history, thorough examination, and methodical workup are essential. Specific management is predicated on identification of the underlying etiology.

摘要

综述目的

本文概述了年轻成年人缺血性卒中的评估与管理,重点关注颈动脉夹层、卵圆孔未闭和高凝状态。

最新发现

年轻患者缺血性卒中的发病率正在上升,尽管原因尚不清楚。年轻缺血性卒中患者比同龄人更有可能在早年死亡。既定的血管危险因素在年轻卒中患者中很常见。最近的研究为夹层和卵圆孔未闭等的治疗提供了依据。在缺血性卒中中检测高凝状态的效用尚不清楚。

总结

年轻成年人缺血性卒中是一个重大的公共卫生问题。该年龄组存在多种缺血性卒中病因。仔细的病史询问、全面的检查和有条不紊的检查至关重要。具体的管理取决于潜在病因的识别。