Moruz Luminita, Käll Lukas
Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Solna, Sweden.
Proteomics. 2014 Jun;14(12):1464-6. doi: 10.1002/pmic.201400036. Epub 2014 May 15.
We here present GradientOptimizer, an intuitive, lightweight graphical user interface to design nonlinear gradients for separation of peptides by reversed-phase liquid chromatography. The software allows to calculate three types of nonlinear gradients, each of them optimizing a certain retention time distribution of interest. GradientOptimizer is straightforward to use, requires minimum processing of the input files, and is supported under Windows, Linux, and OS X platforms. The software is open-source and can be downloaded under an Apache 2.0 license at https://github.com/statisticalbiotechnology/NonlinearGradientsUI.
我们在此展示GradientOptimizer，这是一个直观、轻量级的图形用户界面，用于设计反相液相色谱法分离肽段的非线性梯度。该软件可以计算三种类型的非线性梯度，每种梯度都能优化特定的目标保留时间分布。GradientOptimizer易于使用，对输入文件的处理要求最低，并且在Windows、Linux和OS X平台上均受支持。该软件是开源的，可根据Apache 2.0许可在https://github.com/statisticalbiotechnology/NonlinearGradientsUI下载。
