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感染后肾小球肾炎表现为恶性高血压和血栓性微血管病的非典型病例

Atypical presentation of post infectious glomerulonephritis as malignant hypertension and thrombotic microangiopathy.

作者信息

Vankalakunti M, Malleshappa P, Hussain H, Marilingegouda A

机构信息

Department of Pathology, Manipal Hospital, Bangalore, India.

Department of Nephrology, Adichunchanagiri Institute of Medical Sciences, BG Nagara, Bellur, India.

出版信息

Indian J Nephrol. 2014 Mar;24(2):110-3. doi: 10.4103/0971-4065.127900.

DOI:10.4103/0971-4065.127900
PMID:24701044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3968598/
Abstract

Infection-related glomerulonephritis presents commonly as acute nephritic illness, hypertension, hypocomplementinemia following an episode of pharyngitis or pyoderma. Atypical features like thrombotic microangiopathy (TMA), produced by neuraminidase antigen targeting endothelium have been described rarely. We report a case of TMA secondary to malignant hypertension, coexisting with post infectious glomerulonephritis.

摘要

感染相关性肾小球肾炎通常表现为急性肾炎、高血压、咽炎或脓皮病发作后出现低补体血症。由靶向内皮细胞的神经氨酸酶抗原产生的血栓性微血管病(TMA)等非典型特征很少被描述。我们报告一例继发于恶性高血压并与感染后肾小球肾炎并存的TMA病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/16f2248fc419/IJN-24-110-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/ab5ad0a9f9a1/IJN-24-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/e3dc2d79670f/IJN-24-110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/e6a7ce5b5e66/IJN-24-110-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/16f2248fc419/IJN-24-110-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/ab5ad0a9f9a1/IJN-24-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/e3dc2d79670f/IJN-24-110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/e6a7ce5b5e66/IJN-24-110-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/3968598/16f2248fc419/IJN-24-110-g004.jpg

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本文引用的文献

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Bacterial infection-related glomerulonephritis in adults.成人细菌感染相关性肾小球肾炎。
Kidney Int. 2013 May;83(5):792-803. doi: 10.1038/ki.2012.407. Epub 2013 Jan 9.
2
Postinfectious glomerulonephritis.感染后肾小球肾炎。
Adv Anat Pathol. 2012 Sep;19(5):338-47. doi: 10.1097/PAP.0b013e31826663d9.
3
Post-streptococcal glomerulonephritis is a strong risk factor for chronic kidney disease in later life.链球菌感染后肾小球肾炎是晚年发生慢性肾脏病的一个很强的危险因素。
Kidney Int. 2012 May;81(10):1026-1032. doi: 10.1038/ki.2011.478. Epub 2012 Feb 1.
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Postinfectious glomerulonephritis in the elderly.老年人感染后肾小球肾炎。
J Am Soc Nephrol. 2011 Jan;22(1):187-95. doi: 10.1681/ASN.2010060611. Epub 2010 Nov 4.
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The current state of poststreptococcal glomerulonephritis.链球菌感染后肾小球肾炎的当前状况
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Delay in diagnosis in poststreptococcal glomerulonephritis.
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Acute postinfectious glomerulonephritis in the modern era: experience with 86 adults and review of the literature.现代急性感染后肾小球肾炎:86例成人患者的经验及文献综述
Medicine (Baltimore). 2008 Jan;87(1):21-32. doi: 10.1097/md.0b013e318161b0fc.
8
A rare case of postinfectious glomerulonephritis caused by pneumococcus in an adult patient.一名成年患者因肺炎球菌引起的感染后肾小球肾炎罕见病例。
J Nephrol. 2007 Jan-Feb;20(1):99-102.
9
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