Habaragamuwa Buddhika Widyaratna Peiris, Dissanayaka Palitha
Department of Anesthetists and Critical Care, Base Hospital, Mawanella, Sri Lanka.
Indian J Crit Care Med. 2014 Mar;18(3):181-2. doi: 10.4103/0972-5229.128712.
Although, N-acetylcystein (NAC) has shown benefit in non-acetaminophen related liver failure, it was not well studies in dengue associated severe hepatitis. We report a case of dengue hemorrhagic fever associated severe hepatitis (encephalopathy grade 2-drowsy and intermittent disorientation) treated with NAC resulted in good outcome without hepatic transplantation.
尽管N-乙酰半胱氨酸(NAC)已被证明对非对乙酰氨基酚相关的肝衰竭有益,但在登革热相关的严重肝炎中尚未进行充分研究。我们报告了1例登革出血热相关的严重肝炎(肝性脑病2级——嗜睡和间歇性定向障碍)患者,使用NAC治疗后取得了良好效果,无需进行肝移植。