血栓中入侵伪足的形成：并非如此呆滞。
Invadopodia formation in blood clots: Not so SLUGgish after all.
机构信息
Department of Urology; University of Pittsburgh School of Medicine; Shadyside Medical Center; Pittsburgh, PA USA.
Department of Urology; University of Pittsburgh School of Medicine; Shadyside Medical Center; Pittsburgh, PA USA ; Prostate and Urological Cancers Program; University of Pittsburgh Cancer Institute; Pittsburgh, PA USA.
出版信息
Oncoimmunology. 2014 Jan 1;3(1):e27338. doi: 10.4161/onci.27338.
Blood clotting specifically supports the metastatic dissemination of malignant cells to the lung. We have recently demonstrated that 2 tumor types that are prone to form lung metastases, renal cell carcinoma and soft tissue sarcoma, share specific adhesive mechanisms that support the invasion and colonization of blood clots in the pulmonary vasculature.
血液凝块特别有助于恶性细胞向肺部的转移扩散。我们最近的研究表明，两种容易形成肺转移的肿瘤类型——肾细胞癌和软组织肉瘤——具有特定的黏附机制，支持它们在肺部血管中侵入和定植血栓。
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