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[马赛地区学生和高中生中HPV预防性疫苗接种覆盖率及其影响因素]

[HPV prophylactic vaccine coverage and factors impacting its practice among students and high school students in Marseilles' area].

作者信息

Baudoin A, Sabiani L, Oundjian F, Tabouret E, Agostini A, Courbière B, Boubli L, Carcopino X

机构信息

Service de gynécologie obstétrique, hôpital Nord, assistance publique des hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 20, France.

430, avenue de Lattre-de-Tassigny, 13009 Marseille, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2015 Feb;44(2):126-35. doi: 10.1016/j.jgyn.2014.02.005. Epub 2014 Apr 2.

DOI:10.1016/j.jgyn.2014.02.005
PMID:24703591
Abstract

OBJECTIVES

To assess the coverage of HPV vaccine among young women from Marseilles' area and factors influencing the probability of this vaccination.

MATERIALS AND METHODS

An anonymous survey was conducted among 2124 high school and university students from Marseilles' area, France from December 2011 to May 2012.

RESULTS

Mean age of participants was 20.4years (±SD: 3.3). Only 41.6% participants reported being vaccinated against HPV, of whom 768 (93.3) had completed the 3 injections scheme. Among non-vaccinated respondents, 33.6% acknowledged they would accept a catch-up vaccination. Factors influencing the probability of being vaccinated were young age (AOR: 0.728; 95% CI: 0.681-0.779; P<0.001), socioeconomic and/or education level of parents (AOR: 1.324; 95% CI: 1.006-1.742; P=0.045), information about vaccination (AOR: 24.279; 95% CI: 5.417-108.82; P<0.001) and having a general practitioner (GP) favourable to vaccination (AOR: 68.776; 95% CI: 34.511-137.061; P<0.001). Factors influencing the probability to accept a catch-up vaccination were age (AOR: 1.059; 95% CI: 1.001-1.120; P=0.046), socioeconomic and/or education level of parents (AOR: 1.637; 95% CI: 1.198-2.237; P=0.002) and having a GP favourable to vaccination (AOR: 4.381; 95% CI: 2.978-6.445; P<0.001). Only 35.5% of respondents were aware that screening remains necessary following HPV vaccination.

CONCLUSION

The coverage of HPV vaccine among young women from Marseilles' area is insufficient. Factors influencing the probability of being vaccinated against HPV are age, socioeconomic and/or education level of parents and information regarding vaccination. GP plays a major role in the acceptance of HPV vaccine.

摘要

目的

评估马赛地区年轻女性人乳头瘤病毒(HPV)疫苗接种率及影响接种可能性的因素。

材料与方法

2011年12月至2012年5月,对法国马赛地区2124名高中生和大学生进行了一项匿名调查。

结果

参与者的平均年龄为20.4岁(标准差:3.3)。只有41.6%的参与者报告接种了HPV疫苗,其中768人(93.3%)完成了3剂接种方案。在未接种的受访者中,33.6%承认他们会接受补种疫苗。影响接种可能性的因素包括年龄小(比值比:0.728;95%置信区间:0.681 - 0.779;P<0.001)、父母的社会经济和/或教育水平(比值比:1.324;95%置信区间:1.006 - 1.742;P = 0.045)、疫苗接种信息(比值比:24.279;95%置信区间:5.417 - 108.82;P<0.001)以及有一位支持接种的全科医生(GP)(比值比:68.776;95%置信区间:34.511 - 137.061;P<0.001)。影响接受补种疫苗可能性的因素包括年龄(比值比:1.059;95%置信区间:1.001 - 1.120;P = 0.046)、父母的社会经济和/或教育水平(比值比:1.637;95%置信区间:1.198 - 2.237;P = 0.002)以及有一位支持接种的全科医生(比值比:4.381;95%置信区间:2.978 - 6.445;P<0.001)。只有35.5%的受访者意识到HPV疫苗接种后仍需进行筛查。

结论

马赛地区年轻女性HPV疫苗接种率不足。影响HPV疫苗接种可能性的因素包括年龄、父母的社会经济和/或教育水平以及疫苗接种信息。全科医生在HPV疫苗的接受方面起着主要作用。

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