[急性淋巴细胞白血病缓解期儿童出现泛发性掌跖嗜中性小汗腺汗管炎]
[Palmoplantar neutrophilic eccrine hidradenitis with general extension in a child in remission after acute lymphoblastic leukemia].
作者信息
Salik D, Kolivras A, Sass U, Huybrechts S, Dangoisse C
机构信息
Service de dermatologie, hôpital universitaire des enfants Reine Fabiola (ULB), avenue Jean-Joseph Crocq, 15, 1020 Bruxelles, Belgique.
Service de dermatologie, CHU Saint-Pierre (ULB) , rue Haute, 322, 1000 Bruxelles, Belgique.
出版信息
Ann Dermatol Venereol. 2014 Apr;141(4):285-9. doi: 10.1016/j.annder.2014.01.007. Epub 2014 Feb 25.
BACKGROUND
Neutrophilic eccrine hidradenitis (NEH) is a form of neutrophilic dermatitis characterized by tender erythematous and painful papules involving the trunk, extremities and face. The generalized form is associated with malignant hemopathies. The palmoplantar form occurs in children without any context of malignancy. Histology shows a neutrophilic infiltrate surrounding and infiltrating the eccrine glands associated with vacuolar degeneration and necrosis of the epithelial secretory portion.
PATIENTS AND METHODS
We report the case of a 4-year-old girl with palmoplantar HEN progressing to the generalized form while in remission from acute lymphoblastic leukemia.
DISCUSSION
Progression of HEN from the palmoplantar form to the generalized form has never been published previously in the literature.
背景
嗜中性小汗腺汗管炎（NEH）是一种嗜中性皮肤病，其特征为累及躯干、四肢和面部的压痛性红斑丘疹和疼痛性丘疹。全身性形式与恶性血液病有关。掌跖型发生于无任何恶性肿瘤背景的儿童。组织学显示嗜中性粒细胞浸润围绕并侵入小汗腺，伴有上皮分泌部的空泡变性和坏死。
患者与方法
我们报告了一名4岁女童的病例，该女童患有掌跖型嗜中性小汗腺汗管炎，在急性淋巴细胞白血病缓解期进展为全身性形式。
讨论
嗜中性小汗腺汗管炎从掌跖型进展为全身性形式此前从未在文献中发表过。
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