Neutrophilic eccrine hidradenitis: report of two cases.
作者信息
Kanzaki H, Oono T, Makino E, Arata J, Oda M, Akazai A
机构信息
Department of Dermatology, Okayama University Medical School, Japan.
出版信息
J Dermatol. 1995 Feb;22(2):137-42. doi: 10.1111/j.1346-8138.1995.tb03359.x.
BACKGROUND
Neutrophilic eccrine hidradenitis (NEH) is an uncommon, self-limited dermatosis usually attributed to anti-cancer chemotherapy. It is characterized histologically by necrosis of the eccrine gland and neutrophilic infiltrate.
OBSERVATIONS
We saw NEH in a 5-year-old boy with acute lymphoblastic leukemia and a 4-year-old girl with acute monocytic leukemia. NEH developed after the anti-leukemic chemotherapy including high dose cytarabine. The eruption was composed of vesicles, papules, and plaques.
CONCLUSIONS
Histological findings were compatible with those described in the literature. NEH in our two patients could be attributed to high doses of cytarabine.
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