慢性脑脊髓静脉功能不全及相关多发性硬化症患者颈内静脉疾病的双侧手术重建

Bilateral surgical reconstruction for internal jugular veins disease in patients with chronic cerebrospinal venous insufficiency and associated multiple sclerosis.

作者信息

Spagnolo Salvatore, Scalise Filippo, Barbato Luciano, Grasso Maria Antonietta, Tesler Ugo F

机构信息

Department of Cardiac and Vascular Surgery, Policlinico di Monza, Monza, Italy; Cardiac and Vascular Catheterization Laboratory, Policlinico di Monza, Monza, Italy; CCSVI Research Center, Policlinico di Monza, Monza, Italy.

Cardiac and Vascular Catheterization Laboratory, Policlinico di Monza, Monza, Italy; CCSVI Research Center, Policlinico di Monza, Monza, Italy.

出版信息

Ann Vasc Surg. 2014 Oct;28(7):1793.e1-4. doi: 10.1016/j.avsg.2014.03.012. Epub 2014 Apr 2.

DOI:10.1016/j.avsg.2014.03.012

PMID:24704584

Abstract

Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by morphologic alterations involving efferent cerebral vascular paths. CCSVI has been implicated as a contributing factor to multiple sclerosis (MS) but this theory is highly controversial. We report 3 cases of CCSVI patients with MS who had undergone internal jugular veins (IJVs) angioplasty to restore vessels patency. All patients reported significant symptomatic improvement after angioplasty until symptoms recurred after restenosis of the treated IJVs. Surgical IJVs reconstruction was performed. Patients' symptoms gradually improved and the benefits were maintained at the 1-year follow-up.

摘要

慢性脑脊髓静脉功能不全（CCSVI）是一种血管疾病，其特征是传出性脑血管路径出现形态学改变。CCSVI被认为是多发性硬化症（MS）的一个促成因素，但这一理论极具争议性。我们报告了3例患有MS的CCSVI患者，他们接受了颈内静脉（IJVs）血管成形术以恢复血管通畅。所有患者在血管成形术后均报告症状有显著改善，但在治疗的IJVs再狭窄后症状复发。于是进行了手术性IJVs重建。患者症状逐渐改善，且在1年随访时仍保持疗效。