CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice.
作者信息
Joedicke Jara J, Zelinskyy Gennadiy, Dittmer Ulf, Hasenkrug Kim J
机构信息
Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
出版信息
J Virol. 2014 May;88(9):5200-1. doi: 10.1128/JVI.00312-14.
Abstract
摘要
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CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice.
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本文引用的文献
1
Elimination of friend retrovirus in the absence of CD8+ T cells.
J Virol. 2014 Feb;88(3):1854-5. doi: 10.1128/JVI.03271-13. Epub 2013 Nov 13.
2
CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.
J Virol. 2013 Jun;87(11):6306-13. doi: 10.1128/JVI.00432-13. Epub 2013 Mar 27.
3
Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.
J Immunol. 2011 Oct 1;187(7):3730-7. doi: 10.4049/jimmunol.1101612. Epub 2011 Aug 26.
4
Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors.
J Immunol. 2010 May 1;184(9):4696-707. doi: 10.4049/jimmunol.0903478. Epub 2010 Mar 29.
5
Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirus.
PLoS Pathog. 2009 Aug;5(8):e1000406. doi: 10.1371/journal.ppat.1000406. Epub 2009 Aug 28.
6
The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.
Blood. 2009 Oct 8;114(15):3199-207. doi: 10.1182/blood-2009-03-208736. Epub 2009 Aug 11.
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CD8 is needed for development of cytotoxic T cells but not helper T cells.
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Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.
Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11381-5. doi: 10.1073/pnas.89.23.11381.
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LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice.
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